Irinotecan, sold under the brand name Camptosar among others, is an anti-cancer medication used to treat colon cancer and small cell lung cancer. [8] For colon cancer it is used either alone or with fluorouracil. [8] For small cell lung cancer it is used with cisplatin. [8]

6 天之前 · Irinotecan injection is given together with other medicines (eg, 5-fluorouracil, leucovorin) to treat patients with metastatic cancer (a cancer that has already spread) of the colon or rectum. This medicine is also given to patients with metastatic cancer of the colon or rectum who have received fluorouracil but disease has progressed or recurred.

2024年4月3日 · Irinotecan side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.. Irinotecan may cause serious side effects. Call your doctor at once if you have:

2023年7月21日 · Irinotecan is a medication used to manage and treat a variety of solid tumors. It is in the DNA topoisomerase I inhibitor class of drugs. Also known as CPT-11, irinotecan is used adjunctively with other therapeutic agents against colorectal cancer as a first- or second-line treatment. This activity reviews the indications, action, and contraindications for irinotecan as a …

Irinotecan hydrochloride is also available in a different form called irinotecan sucrosofate. For more information, see the Drug Information Summary for Irinotecan Sucrosofate. More About Irinotecan Hydrochloride. Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.

Irinotecan can cause some people to develop a set of side effects during or within the first 24 hours after having the drug. These side effects include diarrhoea which may be severe. Other symptoms are - sweating, stomach cramps, increased production of saliva, and watery eyes. You may have an injection of atropine before the irinotecan to ...

Irinotecan has been studied in clinical trials in combination with 5-fluorouracil (5-FU) and leucovorin (LV) and as a single agent [see Dosage and Administration (2)]. When given as a component of combination-agent treatment, irinotecan was either given with a weekly schedule of bolus 5-FU/LV or with an every-2-week schedule of infusional 5-FU/LV.

2024年4月2日 · Interrupt irinotecan and reduce subsequent doses if severe diarrhea occurs. Severe myelosuppression may occur. Serious side effects of irinotecan. Along with its needed effects, irinotecan may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. ...

Irinotecan contains a type of sugar called sorbitol. If you have been told by a doctor that you cannot digest some sugars, talk to your cancer doctor before you start treatment. Vaccinations. Doctors usually recommend that people with cancer have vaccinations for flu and for coronavirus (covid). These help reduce your risk of serious illness ...

Irinotecan is given by intravenous (IV, into a vein) infusion. It is used in a variety of chemotherapy regimens. The actual dose and dosing schedule will depend on your treatment regimen, body size, and general health. You may receive anti-nausea medication and anti-diarrheal medication like atropine prior to the irinotecan infusion.