Pathology Outlines - Iron deficiency anemia
2022年3月28日 · Iron deficiency is defined as ferritin 15 ng/mL and transferrin saturation 10% (PLoS One 2020;15:e0232125) Iron deficiency is more prevalent than IDA F > M; common in …
Iron regulatory protein (IRP)–mediated iron homeostasis is ... - AAAS
2022年10月5日 · Our study reveals that IRPs are critically important for granulocyte development and differentiation in the bone marrow (BM), unveiling a previously unrecognized role for iron …
From the marrow to the blood: optimising the diagnosis of iron ...
2024年9月18日 · This study aimed to establish optimal biomarker diagnostic thresholds for ID diagnosis using bone marrow (BM) iron stores as the gold standard and the C-reactive protein …
Iron Deficiency Anemia - American Society of Hematology
2018年2月22日 · Images shown are of several patients with iron deficiency. Blood loss, lack of adequate iron in the diet and malabsorption are all causes. Erythropoiesis in iron deficiency is …
CD71 (transferrin receptor): an effective marker for erythroid ...
Transferrin receptor (CD71) mediates the uptake of transferrin-iron complexes and is highly expressed on the surface of cells of the erythroid lineage. Although CD71 has been used for …
30 Iron Deficiency Anemia (IDA) - Open Education Alberta
(Transport Iron Depletion): – Decreased serum iron and ferritin – Transferrin and TIBC levels increase – Absent iron stores in the bone marrow – Evidence of anemia is not as apparent. …
Interpretation of Iron Studies: Parameters & Characteristics
While not directly measured in most routine iron studies, bone marrow iron stores are the ultimate indicator of total body iron status. Iron Deficiency: Depleted bone marrow iron stores are a …
Absolute and functional iron deficiency: Biomarkers, impact on …
2024年8月10日 · The injection of a hepcidin analog (causing a decrease in plasma iron and leading to iron deficiency) in mice reduces the number of granulocytes in the spleen, blood, …
Iron Deficiency Anemia - SpringerLink
Iron Deficiency Anemia (IDA) is the most common cause of anemia worldwide. IDA impacts cognitive development in children, increases the risk of adverse outcomes in pregnancy, limits …
Deficiency of Antioxidative Paraoxonase 2 (Pon2) Leads to …
Following the isolation of the bone marrow, cells were stained with the antibodies CD71 and Ter119 and analyzed by flow cytometry. The graphs show the percentage of (a) …