The collateral circulation plays a crucial role in maintaining perfusion to brain tissue in ischemic stroke, which prolongs the time window for effective therapies to be provided and ultimately avoids irreversible damage that may lead to worse clinical outcomes.

2022年8月8日 · In this review, we discuss determinants of the collateral circulation in patients with acute ischemic stroke, report on commonly used and emerging neuroimaging techniques for assessing the collateral circulation, and discuss the therapeutic and prognostic implications of the collateral circulation in relation to reperfusion therapies for acute ...

Keywords: collateral circulation; computed tomography; magnetic resonance imaging; reperfusion; stroke. Publication types Research Support, N.I.H., Extramural

2015年10月8日 · Collateral status differs among patients with acute ischemic stroke. Relatively sparse attention has been devoted to the role of baseline collateral circulation in patients with acute ischemic stroke who are candidates for revascularization.

2021年11月16日 · Importance of Collateral Circulation in Ischemic Stroke. Revascularization encompasses all treatment-related improvements in blood flow, including recanalization of the proximal arterial occlusion and reperfusion of the downstream territory.

2020年3月1日 · Collateral circulation is a dynamic system that tends to preserve cerebral perfusion in conjunction with pathophysiologic changes. Recruitment of these anastomotic pathways is a major component of cerebral homeostatic response to ischemia when the primary conduits fail to provide perfusion to critical parts of the brain. 3

2003年7月24日 · Background— The collateral circulation plays a pivotal role in the pathophysiology of cerebral ischemia. Current knowledge of the collateral circulation remains sparse, largely because of prior limitations in methods for evaluation of these diminutive routes of cerebral blood flow.

Cerebral collateral circulation is a network of blood vessels which stabilizes blood flow and maintains cerebral perfusion whenever the main arteries fail to provide an adequate blood supply, as happens in ischemic stroke. These arterial networks are able to divert blood flow to hypoperfused cerebral areas.

2019年2月1日 · Patients with good collateral blood flow benefit up to 24 hours after stroke onset, whereas those with poor collateral flow evidence less or no benefit. However, clues to why collateral flow varies so widely among patients have remained elusive.

2018年5月15日 · Collateral circulation may be imaged spatially and temporally by CT angiography. Successful reperfusion in ischemic stroke is closely tied to the status of collateral circulation. Good collaterals lead to improved stroke outcome with …