Immunoreceptor tyrosine-based activation motif - Wikipedia
An immunoreceptor tyrosine-based activation motif (ITAM) is a conserved sequence of four amino acids that is repeated twice in the cytoplasmic tails of non-catalytic tyrosine-phosphorylated …
ITAM - 百度百科
生物学中，ITAM是免疫受体酪氨酸激活基序（Immunoreceptor tyrosine-based activation motif）的英文缩写，基本组成是：YXXL/V，活化受体与相应配体结合后，在细胞膜相连的一 …
Immunoreceptor Tyrosine Based Activation Motif - an …
The immunoreceptor tyrosine-based activation motif (ITAM) is a highly conserved region in the cytoplasmic domain of signaling chains of adapter proteins and receptors and is a critical …
免疫受体酪氨酸活化基序 - 维基百科，自由的百科全书
免疫受体酪氨酸活化基序（英語： immunoreceptor tyrosine-based activation motif ，缩写ITAM）是一个由十多个氨基酸构成的保守序列，常出现在免疫系统某些细胞的跨膜蛋白的胞 …
The Expanding Role for ITAM-Based Signaling Pathways in …
The immunoreceptor tyrosine-based activation motif (ITAM) is the primary signaling domain used by classical immunoreceptors, such as the antigen receptors on B and T lymphocytes and the …
The many faces of ITAMs: Trends in Immunology - Cell Press
Innate and adaptive immune responses are regulated by receptors that signal through immunoreceptor tyrosine-based activation motifs (ITAMs). The molecular basis of ITAM …
CD3ζ ITAMs enable ligand discrimination and antagonism by …
2023年11月9日 · The T cell antigen receptor (TCR) contains ten immunoreceptor tyrosine-based activation motif (ITAM) signaling sequences distributed within six CD3 subunits; however, the …
Role of ITAM-containing adapter proteins and their receptors …
The immunoreceptor tyrosine-based activation motif (ITAM) is a highly conserved region in the cytoplasmic domain of signaling chains and receptors and is a critical mediator of intracellular …
Emerging roles for ITAM and ITIM receptor signaling in microglial ...
In this review, we summarize the diverse functions employed by microglia in response to Aβ plaques and also discuss the innate immune receptors and intracellular signaling players that …
A role for the ITAM signaling module in specifying cytokine
2014年3月9日 · Immunoreceptor tyrosine-based activation motifs (ITAMs) and ITAM-like adaptors are some of the most widely used conserved signaling modules in leukocytes 1.