2024年12月25日 · ITGA9 (Integrin Subunit Alpha 9) is a Protein Coding gene. Diseases associated with ITGA9 include Hypotrichosis-Lymphedema-Telangiectasia Syndrome and Hennekam Lymphangiectasia-Lymphedema Syndrome 1. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and Integrin Pathway.

Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an Integrin that is …

Integrin alpha-9 is a protein that in humans is encoded by the ITGA9 gene. [5][6][7] Cytogenetic location: 3p22.2 [8] This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion.

整合素 alpha9 (ITGA9) 是研究较少的整合素亚基之一，可促进加速细胞迁移并调节多种生物功能，如血管生成、淋巴管生成、癌细胞增殖和迁移。 在这项工作中，研究了整合素α9 在正常人乳腺组织、原发性乳腺肿瘤和乳腺癌细胞系MCF7 中的表达及其表观遗传调控。

ITGA9 can improve cell migration and regulate various cellular biological functions, such as tumor cell proliferation, adhesion, invasion, and angiogenesis. However, its abnormal expression mechanism in cancer and its specific role in tumor growth and …

ITGA9 level is significantly higher in triple-negative breast cancer (TNBC) than other breast cancer subtypes. Hhigher ITGA9 level is associated with significantly worse metastasis- and recurrence-free survival.

Integrin alpha9 (ITGA9) is one of the less studied integrin subunits that facilitates accelerated cell migration and regulates diverse biological functions such as angiogenesis, lymphangiogenesis, cancer cell proliferation and migration. In this work, integrin alpha9 expression and …

2024年11月2日 · Title: Association study of hypertension susceptibility genes ITGA9, MOV10, and CACNB2 with preeclampsia in Chinese Han population. Integrin alpha9 emerges as a key therapeutic target to reduce metastasis in rhabdomyosarcoma and neuroblastoma.

2025年1月4日 · Reduction of mouse egg surface integrin alpha9 subunit (ITGA9) reduces the egg's ability to support sperm-egg binding and fusion. role for alpha9beta1-EIIIA interactions in wound keratinocyte function. Enables integrin binding activity involved in cell-matrix adhesion. Acts upstream of or within neutrophil chemotaxis.

2022年1月1日 · 根据目前的研究整合分析，整合素α9（itga9）是整合素亚基之一，整合素中itga9的研究较少。 ITGA9可以改善细胞迁移并调节多种细胞生物学功能，如肿瘤细胞增殖、粘附、侵袭和血管生成。