ITP is a rare autoimmune blood disorder that both children and adults can develop. There are 2 forms of ITP: Acute thrombocytopenic purpura. This is the most common type of ITP and mainly affects younger children. Less commonly, it may occur in older children and adults. Symptoms often appear after a virus, such as chickenpox.

Immune thrombocytopenia (ITP) is a rare blood disorder that affects how your blood clots. When your blood can’t clot, you may bruise easily, bleed more than normal when you’re hurt or start bleeding for no reason. Sometimes, ITP goes away without treatment. Other times, it’s a chronic condition, meaning treatment eases symptoms but doesn’t cure it.

2024年10月3日 · Immune thrombotic thrombocytopenic purpura (iTTP) is a rare, life-threatening autoimmune disorder caused by a disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 (ADAMTS13) deficiency.

2025年2月20日 · Thrombotic thrombocytopenia purpura (TTP) is a rare, serious blood disease. There is an acquired/autoimmune form of the disease referred to as immune mediated TTP (iTTP) and a congenital form of the disease (cTTP).

探索奥妥珠单抗、糖皮质激素为基础的联合方案在复发性免疫性血栓性血小板减少性紫癜（iTTP）患者中的疗效与安全性。 回顾性分析2023年1月1日至2024年6月30日苏州大学附属第一医院血液内科收治的4例经过奥妥珠单抗、糖皮质激素为基础联合治疗的复发性iTTP患者。 ...

2023年1月19日 · Immune thrombocytopenic purpura (iTTP) is a near-fatal disease unless immediate treatment is initiated with the current recommended therapies of therapeutic plasma exchange, immune suppression, and caplacizumab. 1, 2 With this regimen, the mortality of iTTP in high-volume centers has been markedly reduced, transforming it instead into a chronic ...

2022年8月4日 · Immune-mediated thrombocytopenic purpura (iTTP) is a thrombotic microangiopathy characterized by an acquired ADAMTS13 deficiency as a result of the presence of an antibody inhibitor of ADAMTS13 leading to the …

Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a rare and potentially lethal disease characterized by fragmentary hemolysis, moderate-to-severe thrombocytopenia, end-organ dysfunction, and severely reduced ADAMTS13 levels (< 10%). Survival in iTTP has improved significantly since t …

免疫性血小板减少（immune thrombocytopenia，ITP）是临床上单发性血小板减少最常见的病因。 ITP以免疫介导的血小板破坏和血小板功能受损为特点。 常见的出血症状包括紫癜（於点和淤 …

2024年10月3日 · Caplacizumab with immunosuppression, but without additional TPE, is an effective and safe treatment strategy for acute iTTP. Immune thrombotic thrombocytopenic purpura (iTTP) is a rare, life-threatening autoimmune disorder caused by a disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 (ADAMTS13) deficiency.