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2020年1月8日 · Mobile genetic elements (MGEs) contribute to bacterial adaptation and evolution; however, high-throughput, unbiased MGE detection remains challenging. We describe …

Allocation of interneurons to their appropriate regions and layers in the neocortex is thought to play important roles for the emergence of higher functions of the neocort... ... that the...

2024年11月12日 · ReaL-MGE enables precise manipulation of numerous large DNA sequences as demonstrated by the simultaneous insertion of multiple kilobase-scale sequences into E. …

2020年1月8日 · Mobile genetic elements (MGEs) contribute to bacterial adaptation and evolution; however, high-throughput, unbiased MGE detection remains challenging. We describe …

2023年10月5日 · Here, we report the development and characterization of a cell therapy alternative for drug-resistant MTLE, which is derived from a human embryonic stem cell line …

2023年6月1日 · Mobile genetic elements (MGEs) are central to horizontal gene transfer (HGT), serving microbes by trafficking adaptive traits between species and strains 1, 2. But MGEs are …

Genetic Strategy for Targeting MGE via In Utero Electroporation (A) Strategy to express Cre-dependent GFP into MGE progenitors via in utero electroporation (IUE) of Nkx2.1Cre …

In this study, we utilize in utero electroporation (IUE) to conduct in vivo fate mapping of cortical interneurons originating from APs or BPs. Remarkably, MGE APs are strongly biased to-ward …

2024年3月5日 · First, using in utero electroporation (IUE) to target the LGE in a Cre recombinase-dependent IS (RosaCAG-LSLFrt-tdTomato-Frt-EGFP) reporter mouse line 18, we found that …