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3 天之前 · The study by Gómez Lumbreras et al 15 reported an ICER of $24 million/QALY for semaglutide and lifestyle modification vs phentermine-topiramate and lifestyle modification. The estimate from the current study for the same comparison was much lower at $100 000/QALY than the estimate from Gómez Lumbreras et al, 15 likely due to the incorporation ...

The Journal of Economic Theory publishes original research on economic theory. It is the most general-interest journal among those specializing in economic theory. It is also one of nine core journals in all of economics. The Journal strives to respond in four months from receipt of the …

2022年10月18日 · Effects of dapagliflozin compared with placebo on outcomes according to frailty index. Models are stratified by diabetes status. HF indicates heart failure.

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Butt et al. examined the effect of dapagliflozin on heart failure (HF) and reduction of serum uric acid levels in patients with and without gout (1). The adjusted hazard ratio (HR) (95% confidence interval [CI]) of dapagliflozin use for the primary end point, presenting the composite of worsening HF or cardiovascular death, was 0.84 (0.66-1.06 ...

2019年2月7日 · Andexanet alfa is a modified recombinant inactive form of human factor Xa developed for reversal of factor Xa inhibitors. We evaluated 352 patients who had acute major bleeding within...

2014年1月1日 · Juvenile hormone (JH) is a critical regulator of insect development and physiology, widely known for its ability to delay metamorphosis. The mechanisms underlying the action of JH have been poorly understood, partly as a …

标致 308 是一款紧凑型轿车，首款标致 308 车型将搭载从 207 车型移植过来的 120 马力 1.6L 直列 4 缸汽油发动机，配备 215/55 R16 的米其林轮胎。 这之后，还有宝马公司提供的 150 马力 …

Juvenile hormone (JH) plays key roles in controlling insect growth and metamorphosis. However, relatively little is known about the JH signaling pathways. ... Wen D, He QY, et al. Juvenile hormone counteracts the bHLH-PAS transcription factors Met and GCE to prevent caspase-dependent programmed cell death in Drosophila. Development. 2009;136: ...