JWH-210 is an analgesic chemical from the naphthoylindole family, which acts as a potent cannabinoid agonist at both the CB 1 and CB 2 receptors, with K i values of 0.46 nM at CB 1 and 0.69 nM at CB 2.

Jwh-210 | C26H27NO | CID 45270396 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

JWH-210 is a lab-made cannabinoid that is utilized in the United States for analyzing wastewater samples to detect synthetic cannabinoids. This compound can be identified at concentrations as low as 10 parts per billion (ppb).

JWH-122 and JWH-210 are naphthoylindolic compounds and act as potent cannabinoid agonists at CB1 and CB2 receptors. According to a structure-activity relationship study, JWH-122 and JWH-210 have a binding affinity at cannabinoid CB1 receptors 60 and 90 times higher than that of THC, respectively.

JWH-210 The Drug Enforcement Administration’s Special Testing and Research Laboratory generated this monograph using structurally confirmed reference material. 1. GENERAL INFORMATION IUPAC Name: (4-ethylnaphthalen-1-yl)(1-pentyl-1H-indol-3-yl)methanone CAS #: 824959-81-1 Synonyms: n/a

Acute adverse effects of JWH-210 typically include central nervous system depression or cerebral seizures, but also signs of sympathomimetic toxicity. Nausea was reported in 80% and typically shows a sudden onset shortly after inhalation, suggesting a central nervous effect possibly mediated by CB 1 receptors.

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JWH 210 (Item No. 10644) is a potent cannabimimetic alkylindole, binding the central cannabinoid and peripheral cannabinoid receptors with K i values of 0.46 and 0.69 nM, respectively. 1 The effects of JWH 210 in whole cells or organisms have not been evaluated. This product is intended for research and forensic applications.

2021年8月19日 · Sixteen volunteers self-administered 1 mg dose of JWH-122 (n = 8) or 2.25 mg mean dose of JWH-210 (range 2-3 mg, n = 8) by inhalation (smoking). Physiological parameters including blood pressure (systolic and diastolic), heart …

JWH-210 is an analgesic chemical from the naphthoylindole family, which acts as a potent cannabinoid agonist at both the CB1 and CB2 receptors. JWH-210 is one of the most potent 4-substituted naphthoyl derivatives in the naphthoylindole series, having a higher binding affinity.