Jak is the main protagonist and titular player character of the Jak and Daxter series, accompanied by his sidekick, Daxter. He is a human male with green-blond hair, cerulean blue eyes, and fair skin.

2024年11月25日 · Janus kinase (JAK) inhibitors are a group of medications that can treat various types of arthritis, including rheumatoid arthritis (RA), cancer, dermatological conditions like atopic dermatitis and alopecia areata, and some bowel conditions …

Jak and Daxter is an action-adventure platformer third-person shooter video game franchise created by Andy Gavin and Jason Rubin and owned by Sony Interactive Entertainment. The series was originally developed by Naughty Dog with a number of installments being outsourced to Ready at Dawn and High Impact Games.

Janus kinase (JAK) is a family of intracellular, non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway. They were initially named "just another kinase" 1 and 2 (since they were just two of many discoveries in a PCR-based screen of kinases), [1] but were ultimately published as "Janus kinase".

2023年10月26日 · Janus kinase (JAK) inhibitors are a group of medicines that help block immune system signals in the body that can lead to swelling (inflammation) and pain in conditions like rheumatoid arthritis, ulcerative colitis, and psoriatic arthritis.

A JAK inhibitor interferes with signals in the body that are thought to cause inflammation. This, in turn, reduces the inflammation that fuels diseases like eczema, psoriatic arthritis, and vitiligo. With less inflammation, the immune system calms down.

2023年12月6日 · JAKs inhibitors are approved to treat of a variety medical conditions, including rheumatoid arthritis, atopic dermatitis (eczema), COVID-19, and certain rare blood cancers of the bone marrow (myelofibrosis).

2024年8月13日 · JAK inhibitors like Xeljanz, Rinvoq, and Opzelura can treat inflammatory conditions and even alopecia. View this list of JAK inhibitors to learn about their various uses.

Janus kinase inhibitors (JAKis) represent a fundamental therapeutic tool for the treatment of patients with immune-mediated inflammatory diseases. Although JAKis are often considered a homogeneous class of drugs whose members are thought to be largely interchangeable, there are significant differences in their efficacy and safety profiles.

JAK, also known as JAK Arms Industries, is a weapon manufacturer in Call of Duty: Modern Warfare, Call of Duty: Mobile and Call of Duty: Modern Warfare III.