2024年8月22日 · Though less serious than some other side effects, JAK inhibitor-associated acne — JAKne, for short — can be a concern for patients.

2024年8月23日 · What is JAKne? “JAKne is not one thing. It is a spectrum of acne and acneiform conditions [seen in patients taking JAK inhibitors],” says Brett King, MD, PhD, an Associate Professor of Dermatology Yale University School of Medicine in New Haven, CT.

2024年8月28日 · Janus kinase (JAK) inhibitors have had game-changing effects for patients with psoriasis, atopic dermatitis, vitiligo, and alopecia areata, but the use of these potent medications has been associated with JAK inhibitor-associated acne (JAKne).

2024年1月8日 · To the Editor: Janus kinase inhibitor-associated acne (JAKne) is recognized as a treatment-emergent adverse event (AE) in patients undergoing therapy with JAK-inhibitors.1 Recent post hoc analyses show that JAKne is typically mild to moderate in severity and can be managed with topical therapies or without intervention.1,2 However, the event ...

Key Points. Question Is there an association between Janus kinase (JAK) inhibitor use and acne?. Findings In this systematic review and meta-analysis of 25 unique phase 2 and 3 randomized clinical trials with 10 839 participants, JAK inhibitors were associated with a 3.83 times higher odds of acne compared with placebo. This association was stronger among those studies conducted for ...

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