2021年8月4日 · Description for Je-Vax. JE-VAX®, Japanese Encephalitis Virus Vaccine Inactivated, is a sterile, lyophilized vaccine for subcutaneous use, prepared by inoculating mice intracerebrally with Japanese encephalitis (JE) virus, "Nakayama-NIH" strain, manufactured by The Research Foundation for Microbial Diseases of Osaka University ("BIKEN ® …

Japanese encephalitis vaccines first became available in the 1930s. [3] One of them was an inactivated mouse brain-derived vaccine (the Nakayama and/or Beijing-1 strain), made by BIKEN and marketed by Sanofi Pasteur as JE-VAX, until production ceased in 2005. The other was an inactivated vaccine cultivated on primary hamster kidney cells (the Beijing-3 strain).

2024年5月15日 · Japanese encephalitis vaccine. IXIARO is given as a two-dose series, with the doses spaced 28 days apart. Adults aged 18–65 years can get the second dose from 7–28 days after the first dose.

Japanese Encephalitis Virus Vaccine (JE-VAX) The JEV vaccine prevents Japanese encephalitis virus infections. This infection results from a mosquito bite. Your provider may recommend this vaccine if you’re traveling to Asia or the western Pacific, and …

2024年5月15日 · Considerations for JE vaccination for travelers. Healthcare providers should advise all travelers to JE-endemic countries to take steps to avoid mosquito bites and discuss the need for vaccination. The discussion should include the risks related to the specific travel itinerary, the likelihood of future travel to countries where JE …

7-valent pneumococcal conjugate vaccine (Prevnar) manufactured by Wyeth (now Pfizer Inc.), hepatitis A vaccine (Havrix 720) manufactured by GSK [Dubischar 2017b], or inactivated mouse brain-derived JE vaccine (JE-VAX) manufactured by Biken (Japan) or phosphate buffered saline with 0.1% aluminum hydroxide [Dubischar-Kastner 2010 (b)].

JE-VAX®, licensed since 1992 and the only licensed vaccine in the USA, Canada and Australia in the 1990ies and early 2000s, was a formalin-inactivated, mouse-brain-derived vaccine, manufactured by the Foundation for Microbial Diseases of Osaka University in Japan with proven protective efficacy. 32 Serious side-effects, such as anaphylaxis ...

2024年8月14日 · 小鼠脑源性疫苗(Japanese Encephalitis-vaccine, JE-VAX)在许多国家已经使用了数十年，但因为超敏反应等一系列副作用，于2005年停止生产。 中国研制的减毒活疫苗SA-14-14-2具有优异的安全性和有效性，在亚洲接种量超过13亿剂，到目前为止，没有报道过明显的副作用。

ABSTRACT. Japanese encephalitis (JE) is a serious public health concern in most of Asia. The disease is caused by JE virus (JEV), a flavivirus transmitted by Culex mosquitoes. Several vaccines have been developed to control JE in endemic areas as well as to protect travelers and military personnel who visit or are commissioned from non-endemic to endemic areas.

2024年12月5日 · In children aged 2–5 years who previously received JE-Vax, 86% were seropositive against the vaccine strain at baseline, and 72–81% were seropositive against 4 wild-type strains at baseline. A dose of Imojev produced seroprotective antibody levels against the vaccine strain in 100% of the children, and against all wild-type strains in 99%.