John Frederick Joseph Cade AO [1][2][3] (18 January 1912 – 16 November 1980) was an Australian psychiatrist who in 1948 discovered the effects of lithium carbonate as a mood stabilizer in the treatment of bipolar disorder, then known as manic depression.

Australian psychiatrist John Frederick Joseph Cade pioneered the use of lithium carbonate to treat manic-depressive disorder (now called bipolar disorder) in patients. The use of the drug revolutionized the treatment of bipolar disorder.

John Frederick Joseph Cade (1912-1980), medical scientist, was born on 18 January 1912 at Horsham, Victoria, son of David Duncan Cade, medical practitioner, and his wife Ellen, née Edwards, both Victorian born. David commanded the 3rd Field Ambulance, Australian Imperial Force, during World War I and was awarded the Distinguished Service Order.

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John Frederick Joseph Cade (1912–1980) was an Australian psychiatrist best known for his discovery of lithium as an effective treatment for bipolar disorder (formerly known as manic-depressive illness). Cade’s breakthrough in the use of lithium transformed the treatment of mood disorders and remains one of the most significant developments ...

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