2021年5月3日 · An Arabidopsis quadruple jox mutant, joxQ, displayed reduced growth, constitutively elevated JA and JA-Ile levels, and enhanced defense against insects and fungi (Caarls et al., 2017). The oxidation of JA to 12-OH-JA can be considered a metabolic shunt that diverts JA from conversion to JA-Ile, the biologically active form of jasmonate ...

2017年5月30日 · Here, we identify four jasmonate-induced oxygenases (JOXs) in Arabidopsis that hydroxylate jasmonic acid to form inactive 12-OH-JA. A mutant that no longer produces the four enzymes hyperaccumulates JA, exhibits reduced growth, and is highly resistant to attackers that are sensitive to JA-dependent defense.

2020年4月1日 · JOXs have been shown to hydroxylate JA and repress resistance to herbivores. For example, joxQ quadruple mutant plants had enhanced resistance to the generalist caterpillar Mamestra brassicae (Caarls et al., 2017). Similarly, Smirnova et al. (2017) found that the same four hydroxylases of JA repress plant defense against the fungal infection.

An Arabidopsis quadruple jox mutant, joxQ, displayed reduced growth, constitutively elevated JA and JA-Ile levels, and enhanced defense against insects and fungi (Caarls

2021年5月3日 · The persistent accumulation of JA inhibits plant growth, and the hydroxylation of JA to 12-hydroxy-JA by JASMONATE-INDUCED OXYGENASEs (JOXs, also named jasmonic acid oxidases) is therefore vital for plant growth, while structural details of …

2020年1月3日 · Our finding that simultaneously silencing four JA hydroxylases in N. attenuata increased plant resistance to the generalist herbivore S. litura is consistent with previous studies that found that Arabidopsis joxQ mutants show enhanced M. brassicae resistance. Importantly, we demonstrate that the enhanced herbivore resistance resulted from ...

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拟南芥中joxQ全基因突变体对灰霉菌的抗性增加 ，水稻中osjoxs突变体JA通路Marker基因的基础表达水平上升，并且对稻瘟病菌的抗性提高 ，这表明在拟南芥和水稻面对灰霉菌和稻瘟病菌侵染时JOXs基因负调控抗病过程。

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Structure-guided analysis of Arabidopsis JASMONATE-INDUCED OXYGENASE (JOX) 2 reveals key residues for recognition of jasmonic acid substrate by plant JOXs . Xin Zhang, Dongli Wang, Joyce Elberse, Linlu Qi, Wei Shi, You-Liang Peng, Robert C. Schuurink, Guido Van den Ackerveken, Junfeng Liu. Molecular Plant.