A genome-wide survey of mutations in the Jurkat cell line
The Jurkat cell line harbors many mutations that are associated with cancer and contribute to Jurkat’s unique characteristics. Genes with damaging mutations in the Jurkat cell line are …
Eltrombopag directly activates BAK and induces apoptosis
2023年7月1日 · Here we report that, in contrast to its function as a BAX inhibitor, Eltro directly binds BAK but induces its activation in vitro. Moreover, Eltro induces or sensitizes BAK …
Raptinal bypasses BAX, BAK, and BOK for mitochondrial outer
2019年7月19日 · Here, we show that the small molecule Raptinal overcomes this limitation by triggering cytochrome c release in a BAX/BAK/BOK-independent manner. Raptinal exerts a …
The Overexpression of Bax Produces Cell Death upon Induction of …
1998年3月27日 · Stably transfected Jurkat T cells were produced in which Bax expression is inducible by muristerone A. The cell death resulting from induction of the overexpression of …
The mechanism of Jurkat cells apoptosis induced by ... - PubMed
The protein expression of Bax and Bcl-2 was examined by western blot. Differentially expressed apoptosis-related proteins were identified based on isobaric tags for relative and absolute …
The course of etoposide-induced apoptosis in Jurkat cells
Jurkat T-lymphocytes lack p53 and Bax but contain p73 and Bid and are killed by etoposide (ETO). With ETO c-abl is phosphorylated and phosphorylated p73 increased. Translocation of …
The mechanism of Jurkat cells apoptosis induced by
2017年2月28日 · Ohara et al. reported that caspase 2, 7 and caspase 2-mediated Bax/Bak translocation were involved in CDT-induced apoptosis in human Jurkat cells . These results …
紫杉醇_细胞凋亡_bcl-2基因家族_细胞株，Jurkat - 百拇医药
2000年6月1日 · 结果 紫杉醇能抑制Jurkat细胞生长，在一定剂量和时间范围内，主要引起细胞凋亡，并显示剂量和时间效应，在这个过程中bax转录及蛋白表达增加，并出现bcl-xs的转录。
A genome-wide survey of mutations in the Jurkat cell line
2025年1月1日 · The Jurkat cell line harbors many mutations that are associated with cancer and contribute to Jurkat’s unique characteristics. Genes with damaging mutations in the Jurkat cell …
A genome-wide survey of mutations in the Jurkat cell line
2018年5月8日 · The Jurkat cell line harbors many mutations that are associated with cancer and contribute to Jurkat's unique characteristics. Genes with damaging mutations in the Jurkat cell …
- 某些结果已被删除