KLF1 - Wikipedia
Krueppel-like factor 1 is a protein that in humans is encoded by the KLF1 gene. The gene for KLF1 is on the human chromosome 19 and on mouse chromosome 8. Krueppel-like factor 1 is …
KLF1 Gene - GeneCards | KLF1 Protein | KLF1 Antibody
2024年12月25日 · KLF1 (KLF Transcription Factor 1) is a Protein Coding gene. Diseases associated with KLF1 include Anemia, Congenital Dyserythropoietic, Type Iva and Fetal …
红细胞生成的转录调控机制研究进展 - 国际输血及血液学杂志
klf1可在红系-巨核系祖细胞及红系各阶段细胞中表达，通过与其他谱系特异性转录因子之间的相互作用，调控红系谱系分化。对人和小鼠造血祖细胞谱系分化的研究发现，klf1与gata1的转录水 …
Krüppel-Like Factor 1 (KLF1), KLF2, and Myc Control a Regulatory ...
Erythroid KLF (EKLF or KLF1) was the first family member to be identified in mice and humans (49) and is a master regulator of definitive erythropoiesis. It is expressed specifically in …
KLF1 KLF transcription factor 1 [ (human)] - National Center for ...
2025年2月8日 · KLF1 and KLF2 positively regulate the embryonic and fetal beta-globin genes through direct promoter binding. Six different KLF1 mutations were identified in 52 of 145 …
The kruppel-like factor (KLF) family, diseases, and physiological ...
2024年2月15日 · Klf1 is involved in erythrocyte development and regulating the developmental transition from fetal hemoglobin to adult hemoglobin by arranging the expression of numerous …
Krüppel样因子1在珠蛋白基因表达调控中的作用 - 国际输血及血液 …
KLF1是一个基本的红细胞系特异性转录因子，由Miller和Bieker 在1993年首次确认。KLF1 C端高度保守，包含3个串联的C2H2锌指序列组成的DNA结合结构域，N端是富含脯氨酸的转录活化 …
Klf1 Kruppel-like transcription factor 1 (erythroid) [ (house mouse)]
2025年2月8日 · KLF1 directly regulates most aspects of terminal erythroid differentiation including alpha-, beta-globin, and heme biosynthesis, coordination of proliferation and anti-apoptotic …
KLF1 KLF transcription factor 1 - NIH Genetic Testing Registry …
2024年4月11日 · Clinical resource with information about KLF1, BLOOD GROUP--LUTHERAN INHIBITOR, Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B …
EKLF/KLF1, a tissue-restricted integrator of transcriptional control ...
Erythroid Krüppel-like factor (EKLF or KLF1) is a transcriptional regulator that plays a critical role in lineage-restricted control of gene expression. KLF1 expression and activity are tightly …