2020年3月7日 · La Gran D - (KGDD) is a broadcast radio station in Portland, Oregon, United States, providing Mexican Grupera, Ranchera and Tejano music.

KGDD (1520 kHz) is an AM radio station broadcasting a Regional Mexican format. Licensed to Oregon City, Oregon, United States, it serves the Portland, Oregon area. The station is …

2016年6月20日 · We found that PTP1B-deficient HER2+ xenografts have increased hypoxia, necrosis and impaired growth. In vitro, PTP1B deficiency sensitizes HER2+ BC lines to …

Alpha-ketoglutarate-dependent hydroxylases are a major class of non-heme iron proteins that catalyse a wide range of reactions. These reactions include hydroxylation reactions, …

Ferrous iron and α-ketoglutarate (αKG)-dependent dioxygenases (αKGDs) are versatile enzymes that use dioxygen as an oxidant to catalyse various reactions via CH bond activation, including …

RNF213 knockdown reverses the effects of PTP1B deficiency on α-KGDDs, NMOC and hypoxia-induced death of HER2 (+) BC cells, and partially restores tumorigenicity. We conclude that …

We discuss the biochemical and transcriptional mechanisms enabling these metabolites to control cell fate and review evidence that nutrient availability shapes tissue-specific fate programs via …

Damage from oxidative stress and mitochondrial dysfunction occur together in many common neurodegenerative diseases. The enzymes that form the mitochondrial α-ketoglutarate …

含有Jumonji C结构域的组蛋白去甲基酶（JMJ）构成了KDM的主要群体，其中大多数在动植物中在进化上是保守的（Lu等，2008； Jambhekar等，2019）。 α-酮戊二酸（α-KG）主要来源 …

α-Ketoglutarate dehydrogenase (KGDH) dynamically regulates Jumonji C-domain-containing histone demethylase (JMJ)-dependent histone demethylation and gene expression in plants. …