
How the Ki-67 Test Is Used in Breast Cancer Treatment - Verywell Health
2025年3月17日 · For breast cancer, Ki-67 is one of the main tumor biomarkers that your healthcare provider will check for when diagnosing, staging, and monitoring the cancer. A higher level of Ki-67 means that the cancer cells are multiplying at a faster rate.
Ki67值越高,预后越不好?一文读懂病理报告“Ki67”|Ki67|淋巴瘤
2022年1月6日 · 有时Ki67百分比用加号表示,ki67 (+),表示阳性细胞比率低于10%;ki67 (++),表示阳性细胞比率在10%-50%之间;ki67 (+++),表示阳性细胞比率高于50%。 一般来说Ki67有三个作用:即判断肿瘤恶性程度;评估患者预后;判断患者化疗是否敏感。 在很多情况下,较高的ki67指数确实对预后有负面的影响, ki67越高,说明恶性度越高,这样的病人往往分期较晚,肿瘤负荷较大;细胞增殖越快,发生基因突变的概率就越高,也就是说产生耐药性的基因 …
【流式学习】 Ki-67 检测细胞增殖protocol - 知乎 - 知乎专栏
Ki-67蛋白是细胞周期相关的一种核蛋白。 Ki67在细胞分裂的G1,S,G2和M期都是表达的,但是M期结束后,Ki-67就会很快降解,G0期的细胞就不表达Ki-67。 处于蓝色部分阶段的细胞,就处于生长期,会被标记到Ki-67的阳性率里面。
Ki-67 (protein) - Wikipedia
The Ki-67 protein (also known as MKI67) is a cellular marker for proliferation, [10] and can be used in immunohistochemistry. It is strictly associated with cell proliferation. During interphase, the Ki-67 antigen can be exclusively detected within the cell nucleus, whereas in mitosis most of the protein is relocated to the surface of the ...
乳腺癌患者Ki-67值越高,复发率越高?很多患者都误会了! - 知乎
Ki-67表达水平是选择化疗的重要因素之一。 对于其他危险因素较低的患者(HR阳性,HER-2阴性,T1N0),若Ki-67≥30%,推荐进行辅助化疗; 若Ki-67≤14%,由于获益不明确,目前并不推荐辅助化疗;
Ki-67 as a prognostic marker according to breast cancer molecular ...
Patients with Ki-67 higher than 15% exhibited higher incidence of metastasis and recurrence than those with Ki-67 less than 15% (P = 0.000). Conclusions: Ki-67 may be considered as a valuable biomarker in breast cancer patients.
Ki-67 as a Prognostic Biomarker in Invasive Breast Cancer
In breast cancer development, the expression of Ki-67 is strongly associated with cancer proliferation and is a known indicator of prognosis and outcome. Ki-67 expression levels are also useful to inform treatment decision making in some cases. As a result, routine measurement of Ki-67 is now widely performed during pathological tumour evaluation.
最全Ki67解读!从诊断到治疗再到预后,你想知道的都在这!@Me…
2023年5月24日 · Ki-67是一种细胞增殖标志物,可以检测细胞周期中的细胞比例。Ki-67的阳性率越高,说明肿瘤细胞处于生长周期的比例越大,肿瘤的生长速度越快。 例如,某患者的Ki-67检测结果是30%阳性。
Ki-67 and breast cancer prognosis: does it matter if Ki-67 level is ...
This study aimed to identify the association between Ki-67 level and the prognosis of patients with breast cancer, regardless of the timing of Ki-67 testing (using preoperative biopsy vs. postoperative specimen). A total of 4177 patients underwent ...
Ki67值越高,预后越不好?一文读懂病理报告「Ki67」-MedSci.cn
2024年10月14日 · 本文介绍 Ki67 与细胞分裂周期关系及高表达意义,阐述在不同肿瘤中高 Ki67 值意义不同,指出其并非预后唯一指标,肿瘤预后与多种因素有关。 一、Ki67与细胞分裂周期. Ki67的由来. Ki67是一种存在于细胞核中的蛋白,Ki是源于发现它的城市是德国基尔市(Kiel),67这个数字来源于实验编号。 有研究人员发现这个蛋白的数量和细胞的分裂周期有非常紧密的联系。 人体的细胞分裂周期分为G1,S,G2和M期,当M期,即有丝分裂期结束后, …