2024年12月25日 · KIF5A (Kinesin Family Member 5A) is a Protein Coding gene. Diseases associated with KIF5A include Spastic Paraplegia 10, Autosomal Dominant and Amyotrophic …

Kinesin family member 5A is a protein that in humans is encoded by the KIF5A gene. It is part of the kinesin family of motor proteins. [5] [6] [7] This gene encodes a member of the kinesin …

2023年6月29日 · Using postmortem tissue and super-resolution structured illumination microscopy in cell-based perturbation platforms, we provide evidence that KIF5A is present in …

2024年9月27日 · Mutations targeting distinct domains of the neuron-specific kinesin KIF5A associate with different neurodegenerative/neurodevelopmental disorders, but the molecular …

These results provide an insight into the molecular mechanisms of KIF5A, which regulate inhibitory neural transmission and KIF5A deletion causes epilepsy. The results obtained …

Biased expression in brain (RPKM 141.3) and adrenal (RPKM 5.1). 该基因编码驱动蛋白家族的成员。 该家族的成员是多亚基复合体的一部分，该复合体在细胞内细胞器运输中起着微管马达 …

2025年2月9日 · Title: A human proteogenomic-cellular framework identifies KIF5A as a modulator of astrocyte process integrity with relevance to ALS. Road-blocker HSP disease mutation …

Using a large-scale genome-wide association study and exome sequencing, we identified KIF5A as a novel gene associated with ALS. Our data broaden the phenotype resulting from …

2012年12月6日 · KIF5A regulated neuronal surface expression of GABA(A)Rs via an interaction with GABARAP. These results provide an insight into the molecular mechanisms of KIF5A, …

2024年9月27日 · Mutations targeting distinct domains of the neuron-specific kinesin KIF5A associate with different neurodegenerative/neurodevelopmental disorders, but the molecular …