
Killer-cell immunoglobulin-like receptor - Wikipedia
Killer-cell immunoglobulin-like receptors (KIRs), are a family of type I transmembrane glycoproteins expressed on the plasma membrane of natural killer (NK) cells and a minority of …
Frontiers | Killer Ig-Like Receptors (KIRs): Their Role in NK Cell ...
2019年5月27日 · KIR gene family is characterized by an extraordinary high degree of diversity, which arises from variability in KIR gene content, due to differences in both presence/absence …
KIR3DL2:杀伤细胞免疫球蛋白样受体(KIR)家族蛋白,T细胞淋 …
2024年2月28日 · 杀伤细胞免疫球蛋白样受体(Killer Cell Immunoglobulin-like Receptors, KIR,即CD158)是一个由14个多态性基因编码的受体家族(KIR2DL1 、 2DL2 、 2DL3 、 2DL4 …
NK细胞表面免疫检查点受体KIRs知多少 - 知乎 - 知乎专栏
2023年2月24日 · 杀伤细胞免疫球蛋白样受体 (KIR)家族是一类高度多态性的分子,主要表达在一些NK细胞和T细胞的表面,可分为多个亚型。 可为激活性KIRs (aKIRs)和抑制性KIRs (iKIRs)两 …
浅谈NK细胞受体 KIR的功能与临床意义 - 搜狐
2021年2月2日 · 杀伤细胞免疫球蛋白样受体(KIRs)在记忆性T细胞和NK细胞上表达,是NK细胞功能的关键调节因子。 KIR及其配体MHC-I类(HLA-A、-B、-C)分子具有高度多态性,特殊 …
The KIR Gene Cluster - NCBI Bookshelf - National Center for ...
2003年5月28日 · The KIR locus, containing a family of polymorphic and highly homologous genes, maps to chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The …
IPD-KIR Database - EMBL-EBI
Many KIR haplotypes have been defined by family segregation studies (19, 20, 21). Based on their gene content, KIR genotypes can be divided into two broad haplotypes termed A and B. …
The KIR gene family: life in the fast lane of evolution
2004年12月16日 · A hallmark of human NK cells is the expression of HLA class I-specific killer-cell immunoglobulin-like receptors (KIR). An interesting facet of the KIR family is the unusual …
Revealing complete complex KIR haplotypes phased by long …
2017年6月1日 · We present a unique approach to haplotype the KIR loci using single-molecule, real-time (SMRT) sequencing. Using this method, we have—for the first …
KIR Family Research Area: R&D Systems
The KIR family is composed of at least 15 members expressed by natural killer (NK) cells and a subset of T cells in primates only. KIR proteins are named based on the number of …
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