Killer-cell immunoglobulin-like receptors (KIRs), are a family of type I transmembrane glycoproteins expressed on the plasma membrane of natural killer (NK) cells and a minority of …

2024年12月25日 · KIR3DL1 (Killer Cell Immunoglobulin Like Receptor, Three Ig Domains And Long Cytoplasmic Tail 1) is a Protein Coding gene. Diseases associated with KIR3DL1 include …

2019年5月27日 · KIR Genes Display an Extraordinary Level of Polymorphism. KIR gene family is characterized by an extraordinary high degree of diversity, which arises from variability in KIR …

2003年5月28日 · KIR genes are tandemly arrayed over about 150 kb, with the remarkable feature that gene content varies between haplotypes. The discovery of KIR has also imparted an …

2024年2月28日 · 杀伤细胞免疫球蛋白样受体（Killer Cell Immunoglobulin-like Receptors, KIR，即CD158）是一个由14个多态性基因编码的受体家族（KIR2DL1 、 2DL2 、 2DL3 、 2DL4 …

KIR genes are classified as belonging to one of three groups according to their structural features: 1) Type I KIR2D genes, which encode two extra-cellular domain proteins with a D1 and D2 …

The IPD-KIR Database provides a centralised repository for human KIR sequences. Killer-cell Immunoglobulin-like Receptors (KIR) have been shown to be highly polymorphic at the allelic …

2017年6月1日 · We present a unique approach to haplotype the KIR loci using single-molecule, real-time (SMRT) sequencing. Using this method, we have—for the first …

2025年3月4日 · Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and …

4 天之前 · High KIR gene density and sequence similarity may impact recombination rates. In most organisms, an elevated recombination rate is positively correlated with gene density. …