KIF18A Gene - GeneCards | KI18A Protein | KI18A Antibody
2024年12月25日 · KIF18A (Kinesin Family Member 18A) is a Protein Coding gene. Diseases associated with KIF18A include Goldberg-Shprintzen Syndrome. Among its related pathways …
KIF18A - Wikipedia
Kinesin family member KIF18A is a human protein encoded by the KIF18A gene. [5][6] It is part of the kinesin family of motor proteins. KIF18A is a plus-end directed motor protein, and migrates …
81930 - Gene ResultKIF18A kinesin family member 18A [ (human)]
2025年2月8日 · Kinesin Family Member-18A (KIF18A) Promotes Cell Proliferation and Metastasis in Hepatocellular Carcinoma. KIF18A inactivates hepatic stellate cells and alleviates liver …
Small-molecule inhibition of kinesin KIF18A reveals a mitotic ...
2023年12月27日 · Our KIF18A inhibitors have minimal detrimental effects on human bone marrow cells in culture, distinct from other anti-mitotic agents. In mice, inhibition of KIF18A leads to …
KIF18A inhibition: the next big player in the search for cancer ...
2024年11月24日 · Kinesin-like protein 18A (KIF18A) is a member of the kinesin family of molecular motor proteins, which utilise energy from the hydrolysis of adenosine triphosphate …
Therapeutic targeting of the KIF18A motor protein in cancers with ...
2024年1月24日 · Pharmacological inhibition of the mitotic kinesin KIF18A selectively exploits a mitotic vulnerability for which cancer models with CIN are enriched, which leads to robust anti …
KIF18A | Insilico Medicine
ISM developed an AI-designed KIF18A inhibitor with a novel macrocyclic scaffold. This inhibitor exhibited potent anti-proliferation activities in cancer cell lines and CDX models with CIN …
KIF18A as a potential biomarker to distinguish different ... - Springer
2024年3月15日 · KIF18A (Kinesin Family Member 18A), a plus-end directed microtubule depolymerase kinesin which regulates microtubule dynamics, chromosome congression and …
Novel KIF18A Inhibitors for Treating Cancer - PMC - National …
2020年6月25日 · KIF18A is believed to influence dynamics at the plus end of kinetochore microtubules to control correct chromosome positioning and spindle tension. Depletion of …
Integrative analysis of KIF4A, 9, 18A, and 23 and their clinical ...
2019年3月14日 · Gene Set Enrichment Analysis (GSEA) revealed that high mRNA expression of KIF4A, 18A, and 23 in LGG and GBM patients showed significant positive correlations with the …