2023年4月24日 · To this end, we have integrated a variety of tools into one harmonized R/Shiny database called MTSviewer (https://neurobioinfo.github.io/MTSvieweR/), which combines MTS …

2013年4月10日 · Inhibition of kynurenine 3-monooxygenase (KMO), an enzyme in the eukaryotic tryptophan catabolic pathway (that is, kynurenine pathway), leads to amelioration of...

Kynurenine 3-monoox- ygenase (KMO) has a high affinity for kynurenine, suggesting that KMO metabolizes most of the available kynurenine into the neurotoxic agent 3-hydroxykynurenine...

Overall, MTSviewer is a platform that can be used to interrogate MTS mutations and their potential effects on import and proteolysis across the mitochondrial proteome. Click on the …

kmo是做主成分分析的效度检验指标之一,以前的文献中写说,kmo在0.9以上，非常合适做因子分析；在0.8-0.9之间，很适合；在0.7-0.8之间，适合；在0.6-0.7之间，尚可；在0.5-0.6之间，表 …

The C-MTS of KMO is predicted as helical, solvent-accessible, and is distinct from the folded domain of KMO. Arg452 is highlighted as a variant of interest (Arg452Cys).

Kynurenine-3-monooxygenase (KMO) is a mitochondrial enzyme involved in the eukaryotic kynurenine pathway (KP), which is the major catabolic route of tryptophan. KMO can convert …

2022年1月2日 · Under normal physiological conditions, the kynurenine pathway (KP) plays a critical role in generating cellular energy and catabolizing tryptophan. Under inflammatory …

The C-MTS of KMO is predicted as helical, solvent-accessible, and is distinct from the folded domain of KMO. Arg452 is highlighted as a variant of interest (Arg452Cys). PUSL1 contains a …

2024年6月19日 · 线粒体定位信号（mitochondrial targeting signal, MTS）是一段特定的氨基酸序列，指导新合成的蛋白质从细胞质运输到线粒体。 MTS通常位于蛋白质的N端，通过识别和结 …