Quinine is a medication used to treat malaria and babesiosis. [5] . This includes the treatment of malaria due to Plasmodium falciparum that is resistant to chloroquine when artesunate is not available. [5][6] While sometimes used for nocturnal leg cramps, quinine is not recommended for this purpose due to the risk of serious side effects. [5] .

2024年3月25日 · Quinine is used to treat uncomplicated malaria, a disease caused by parasites. Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Quinine will not treat severe forms of malaria, and it should not be taken to prevent malaria.

金基仁（游戏ID：Kiin），1999年5月28日出生于韩国首尔， [4] 《英雄联盟》职业选手，司职上单，效力于 Gen.G。 [2] 金基仁于2017年加入EEW战队开启自己的职业生涯，曾先后效力于AFs（2022年更名为KDF）、KT等战队。 在2018年跟随AFs战队获得LCK春季赛亚军、亚洲洲际赛亚军、LCK夏季赛季军、亚洲运动会亚军、英雄联盟全球总决赛八强，在2020年获得2019KeSPA杯冠军以及FMVP [2]，在2024年获得2024LCK春季赛冠军以及FMVP。 [47] …

Quinine, an alkaloid, acts by interfering with the growth and reproduction of the malarial parasites, which inhabit the red blood cells (erythrocytes). Administration of quinine dramatically improves the condition of a person with malaria; the parasites promptly disappear from the blood, and the symptoms of the disease are quickly alleviated.

Quinine remains an important anti-malarial drug almost 400 years after its effectiveness was first documented. However, its continued use is challenged by its poor tolerability, poor compliance with complex dosing regimens, and the availability of more efficacious anti-malarial drugs.

Kinins are short-lived peptides that cause pain sensation, arteriolar dilation, increase vascular permeability and cause contractions in smooth muscle. Kinins transmit their effects through G protein-coupled receptors. [5] Kinins act on axons to block nervous impulses, which leads to distal muscle relaxation.

2011年5月24日 · Quinine remains an important anti-malarial drug almost 400 years after its effectiveness was first documented. However, its continued use is challenged by its poor tolerability, poor compliance with complex dosing regimens, and the availability of more efficacious anti-malarial drugs.

Generic Name Quinine DrugBank Accession Number DB00468 Background. An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633.

2022年2月10日 · Standard dosage regimens of quinine formulated for adult patients with uncomplicated and complicated malaria have been applied for clinical uses in children, pregnant women, and elderly. Since these populations have anatomical and physiological differences from adults, dosage regimens formulated for adults may not be appropriate.

KLK又称 血管舒缓素，是 激肽系统 的主要限速酶，它是一组存在于多数组织和体液中的 丝氨酸 蛋白酶，是一种 肽链 内切酶。 它特异性的在碳末端切割底物肽，可裂解 激肽原 释放具有活性的激肽，由激肽发挥对 心血管系统 及肾脏功能的调节作用。 KLK分为两大类：血浆KLK和组织KLK，分别由前 激肽 释放酶（pre?kallikrein）和KLK前体（prokallikrein）转换而来。 它们在分子量、底物、免疫学特性、 基因结构 和释放的激肽种类方面有很大差异。 血浆KLK又称Fletcher因子， …