2007年2月20日 · Here we show that KYP-dependent H3K9me2 is found at non-CG methylation sites in addition to those rich in CG methylation. Furthermore, we show that the SRA domain …

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2016年2月5日 · This r-KYP 2 O 7 exhibits an open framework constructed by 4- and 6-membered polyhedral rings, which differs a lot from the known ɑ-KYP 2 O 7 and β-KYP 2 O 7. The …

2014年8月7日 · We report on the structure of KYP in complex with methylated DNA, substrate H3 peptide, and cofactor SAH, thereby defining the spatial positioning of the SRA domain relative …

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2007年2月20日 · These data suggest that DNA methylation is required for the recruitment or activity of KYP and suggest a self-reinforcing loop between histone and DNA methylation. …

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