Coupling liquid chromatography (LC) with high-resolution NMR (LC-NMR) aims to simplify the NMR analysis of mixtures by detecting successively the analytes in the course of the elution [72].

液相核磁共振连用,这种新近发展起来的前沿分析技术,由于它比其他技术能提供更充分的结构信息,从而在现代新药的发现平台中居于非常重要的地位.本文综述了液相核磁共振连用技术(lc-nmr) …

2021年1月6日 · Liquid chromatography (LC)–nuclear magnetic resonance (NMR) combines the advantage of the outstanding separation power of liquid chromatography (LC) and the superior …

applications of hyphenated NMR as LC-NMR and LC-MS-NMR in industry and academia, such as to natural products, degradation products, impurity characterization, drug metabolism, food …

The on-line coupling of high-performance liquid chromatography (HPLC) principles to high-resolution NMR spectrometers offers a powerful tool for analyzing and characterizing complex …

2014年2月14日 · Combined liquid chromatography/nuclear magnetic resonance spectroscopy (LC/NMR) was proposed over 20 years ago, but did not capture the imagination of …

2021年8月25日 · The potential of on-line trace enrichment combined with column liquid chromatography–nuclear magnetic resonance detection (LC–NMR) is demonstrated for the …

LC-NMR is very suitable for the detection of complex metabolites in biological samples and the identification of potential markers. LC-NMR can study metabolites at the molecular level, and …

2003年7月15日 · Nuclear magnetic resonance spectroscopy (NMR) is arguably the most versatile analytical platform for complex mixture analysis. Specifically, interfacing liquid chromatography …

LC-NMR, as the name implies, is a directly combined system of HPLC and NMR. Its main features are high sensitivity and reduced separation steps, which make it a powerful tool for …