Microtubule-associated proteins 1A/1B light chain 3B (hereafter referred to as LC3) is a protein that in humans is encoded by the MAP1LC3B gene. [5] LC3 is a central protein in the …

2024年12月25日 · MAP1LC3A (Microtubule Associated Protein 1 Light Chain 3 Alpha) is a Protein Coding gene. Diseases associated with MAP1LC3A include Skin Amelanotic …

Microtubule-associated protein 1A/1B-light chain 3 (LC3) is a soluble protein with a molecular mass of approximately 17 kDa that is distributed ubiquitously in mammalian tissues and …

LC3/Atg8 被具有蛋白内切酶活性的 Atg4 在羧基端剪切，生成胞浆型 LC3-I。 在自噬形成时，胞浆型LC3-I通过 Atg7 和 Atg3 （分别对应泛素激活酶E1和泛素结合酶E2）参与的类泛素样反应， …

2025年2月16日 · Gene and protein expression of mTOR and LC3 in hepatocellular carcinoma, colorectal liver metastasis and ""normal"" liver tissues. A PI3K-WIPI2 positive feedback loop …

2015年9月17日 · LC3s (MAP1-LC3s) are structural proteins of autophagosomal membranes. The human LC3 gene family has three members, LC3A, LC3B and LC3C, whilst two variants of the …

2025年2月8日 · Macrophage LC3-associated phagocytosis is an immune defense against Streptococcus pneumoniae that diminishes with host aging. STING directly activates …

2020年10月18日 · The microtubule-associated protein 1A/1B light chain 3B (MAP1LC3B or LC3B) is commonly analyzed as a key marker for autophagosomes and as a proxy for autophagic …

2025年2月16日 · LC3B is lipidated to large lipid droplets during prolonged starvation for noncanonical autophagy. Alterations of ATG4A and LC3B in neurons derived from Alzheimer's …

In this punctum, we discuss our recent findings about the essential role for nuclear LC3 in starvation-induced autophagy. During nutrient-rich conditions, LC3 is distributed in an …