2023年7月21日 · Generally, low-density lipoprotein (LDL) particle size can be inferred from the LDL cholesterol concentration to total apolipoprotein B concentration ratio (LDL-C/ApoB ratio, hereinafter called LAR), which is a good predictor of cardiovascular disease.

2023年2月7日 · Low density lipoprotein (LDL) cholesterol—also known as the “bad” cholesterol—is often used as an indicator of heart disease and stroke risks. But some emerging evidence suggests that a protein named apolipoprotein b (apoB) is an even more accurate marker that can identify potential high-risk patients.

While LDL, the major cholesterol-carrying serum lipoprotein, is the primary therapeutic target for management and prevention of atherosclerotic cardiovascular disease, there is strong evidence that apoB is a more accurate indicator of cardiovascular risk than either total cholesterol or …

该基因产物是乳糜微粒和低密度脂蛋白（ldl）的主要载脂蛋白，是ldl受体的配体。 它在血浆中以两种主要的亚型apoB-48和apoB-100出现：前者仅在肠道合成，后者在肝脏合成。

2024年8月16日 · By far the most abundant apoB-containing lipoprotein particle in the circulation is LDL. ApoB and LDL-C levels correlate closely in populations; however, the lipid composition and size of LDL particles can vary greatly between individuals and even within an individual from one measurement to another. 8, 9 While there is a high degree of ...

2024年4月8日 · 载脂蛋白B(apoB) 是 LDL中含量最多的蛋白质，90%以上apoB 存在于 LDL中。apoB具有调 节肝脏内外细胞表面LDL 受体与血浆 LDL 之间平衡的作用，对肝脏合成 VLDL 有调节作用。apoB 的作用成分是apoB-100, 还有其降解产物 apoB-48、apoB-75、apoB-41 和 apoB-36 …

Apolipoprotein B (ApoB) is a crucial structural protein found in atherogenic lipoproteins, including low-density lipoprotein (LDL), very low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), and lipoprotein(a) [Lp(a)]. Unlike other lipid markers such as LDL-C, which measure cholesterol content, ApoB provides a direct count of the number of …

LDL-C是apoB脂蛋白在LDL阶段某个时刻所携带的胆固醇，是一个“静态”的值，相对于动态代谢过程，LDL-C并不等同于LDL形式的apoB脂蛋白，而是一个估计值。

2024年11月1日 · 载脂蛋白B（ApoB）代表循环中致动脉粥样硬化脂蛋白颗粒的总浓度，与低密度脂蛋白胆固醇（LDL-C）相比，可更准确地反映脂蛋白的致动脉粥样硬化负荷。 近期，美国国家脂质协会（NLA）发布了ApoB在成人心血管风险临床管理中的作用临床专家共识，强调了ApoB在成人心血管风险管理中有重要作用，以期为临床提供指导。 本文汇总了共识的要点内容，以飨读者。 什么是ApoB？ ApoB是所有致动脉粥样硬化脂蛋白的主要结构蛋白，是低密度脂蛋白（LDL） …

2025年3月18日 · Multiple components of LDL/oxLDL particles including lipids [74, 75] and apolipoproteins (e.g., apoB and apoE) [76, 77] have been reported to be able to interact with LDL/oxLDL receptors , which may partially contribute to their relatively high LDL/oxLDL–LDLR/CD36 interaction forces.