Leucine-rich, glioma inactivated 1, also known as LGI1, is a protein which in humans is encoded by the LGI1 gene. [5] . It may be a metastasis suppressor. The leucine-rich glioma inactivated …

lgi1 是一种相对分子质量为60 kd的神经元 分泌蛋白，因其最初从胶质瘤细胞中分离出来而 得名[11]。大脑中的lgi1 主要分布于海马和颞叶皮 层，表达在神经元轴突和谷氨酸能突触的起始 …

一、LGI1：富含亮氨酸胶质瘤灭活蛋白1(Leucine-rich glioma inactivated 1, LGI1)与电压门控钾通道形成复合物(VGKC复合物)，可控制膜兴奋性；LGI1是一种分泌性突触蛋白，与ADAM22/23 …

LGI1 (Leucine-rich glioma-inactivated 1) antibody encephalitis is an autoantibody mediated form of limbic encephalitis. It is the most common antibody-mediated encephalopathy in those over …

2024年12月25日 · LGI1 (Leucine Rich Glioma Inactivated 1) is a Protein Coding gene. Diseases associated with LGI1 include Epilepsy, Familial Temporal Lobe, 1 and Autosomal Dominant …

2021年12月30日 · Leucine-rich, glioma inactivated 1 (LGI1) is a secreted glycoprotein, mainly expressed in the brain, and involved in central nervous system development and physiology. …

2021年12月1日 · In this review, we will focus on LGI1 binding partners, “A Disintegrin And Metalloprotease (ADAM) 22 and 23”, the complex they form at the synapse, and will discuss …

4 天之前 · LGI1 is a 60-kDa secreted neuronal protein that consists of the N-terminal leucine-rich repeat (LRR) domain and the C-terminal epitempin-repeat (EPTP) domain . Mutations in the …

The brain MRI in LGI1 antibody encephalitis cases may be normal or show increased T2 signal in bilateral temporal lobes, as was seen in our patient. 14,15 Most cases of LGI1 encephalitis are …

2025年2月25日 · Screening for anti-LGI1 antibodies in patients with neuropsychiatric systemic lupus erythematosus (NPSLE) is crucial when limbic encephalitis presents, as it enables timely …