
Liquid–liquid phase separation in human health and diseases
2021年8月2日 · Recent studies have revealed evidences that indicate that LLPS plays a vital role in human health and diseases. In this review, we describe our current understanding of LLPS …
技术专题 | 液-液相分离 (LLPS):现代生物医学中的新前沿【珍藏】 …
液-液相分离(Liquid-Liquid Phase Separation, LLPS)是指在细胞内某些生物大分子(如蛋白质和RNA)通过相互作用,形成具有不同组分和性质的相分离液滴 [1]。 这些液滴类似于油滴在水 …
Liquid-liquid phase separation in human diseases: Functions, …
2024年12月1日 · In this review, we introduce the insights and findings on the formation, regulation and function of LLPS. The role of LLPS in human diseases, including cancer, …
Liquid-liquid phase separation (LLPS) in cellular physiology and …
This review will summarize the principle and components of LLPS, and describe how LLPS regulate these numerous biological processes and disruption of LLPS would cause disease …
Liquid-liquid phase separation: Fundamental physical principles ...
2023年12月1日 · This review offers a concise overview of LLPS in soft matter, emphasizing its relevance in soft material engineering. We delve into fundamental mechanisms, focusing on …
The role of liquid-liquid phase separation in the disease …
2024年11月1日 · LLPS describes a phenomenon that different components in cells collide and fuse with each other to form droplets, so that some components are wrapped in droplets and …
Liquid-liquid phase separation: Orchestrating cell ... - Cell Press
2021年10月21日 · LLPS plays a role in two important branches of TCR signaling: the linker for activation of T cells (LAT)-Grb2-Son of sevenless (Sos1) axis and the Nck-neural Wiskott …
Liquid-liquid phase separation (LLPS) in cellular physiology and …
2021年8月15日 · Liquid-liquid phase separation (LLPS) has emerged as a mechanism that has been used to explain the formation of known organelles (e.g. nucleoli, promyelocytic leukemia …
Open questions on liquid–liquid phase separation
2023年2月3日 · Liquid-liquid phase separation (LLPS) underlies the formation of intracellular membraneless compartments in biology and may have played a role in the formation of …
Liquid-liquid phase separation in human health and diseases
2021年8月2日 · Emerging evidence suggests that liquid-liquid phase separation (LLPS) represents a vital and ubiquitous phenomenon underlying the formation of membraneless …