The levonorgestrel-releasing intrauterine system (LNG-IUS) is a safe, effective and acceptable form of contraception used by over 150 million women worldwide. It also has a variety of noncontraceptive benefits including treatment for menorrhagia, …

2024年6月18日 · Levonorgestrel is a female hormone that can cause changes in your cervix and uterus. Levonorgestrel intrauterine system or intrauterine device (IUD) is placed in the uterus where it slowly releases the hormone. Levonorgestrel intrauterine system is …

2024年9月16日 · What is a LNG-IUD? The LNG-IUD is a small, flexible, plastic device which sits inside the womb (uterus). There are two threads attached to it which pass out through the neck of the womb (cervix) and lie in your vagina (see diagram below). These allow you to check it is still there. They also mean it can be removed easily.

The levonorgestrel-releasing intrauterine system (LNG IUS) provides a long-acting, highly effective, and reversible form of contraception, with a pearl index of 0.18 per 100 women-years.

2022年4月29日 · We found 4 serious 52-mg LNG-IUS--related TEAEs that led to discontinuation, namely uterine perforation (n=2), embedded device (n=1), and ectopic pregnancy with contraceptive device (n=1).

The LNG-IUS targets the endometrium directly by releasing of LNG. This results in the high local LNG concentrations that cause uniform suppression of endometrial proliferation, inactive histology, thin epithelium, and decidualization of the stroma. LNG-IUS decreases the menstrual blood loss and pain by the suppression of endometrial proliferation.

Levonorgestrel is the progestin hormone released by the IUS, provided locally in the uterus, with an initial release rate of 20 micrograms per day. The LNG IUS functions by suppressing the growth of the uterine wall, reducing fertility, thickening cervical …