Brain endothelial GSDMD activation mediates inflammatory BBB
2024年4月17日 · Single-cell RNA-sequencing analysis reveals that brain endothelial cells (bECs), which express high levels of GSDMD, have a prominent response to circulating LPS. LPS …
A body–brain circuit that regulates body inflammatory responses
2024年5月1日 · We used lipopolysaccahride (LPS), a canonical immune stimulus derived from the outer membrane of Gram-negative bacteria to elicit innate immune responses 28.
Fibroblast growth factor 10 alleviates LPS-induced acute
2024年11月14日 · Experiments in vitro confirmed that FGF10 could elevate macrophage M2 marker ARG1 expression through the JAK2/STAT3 pathway. FGF10 ameliorates acute LPS …
STAT3 blockade ameliorates LPS-induced kidney injury through …
2024年10月4日 · Lipopolysaccharide (LPS) from Gram-negative bacteria is a potent inducer of the L-AKI mouse model. In renal tubular epithelial cells, LPS triggers inflammatory cascades via …
Repeated LPS induces training and tolerance of microglial …
2024年9月20日 · Repeated LPS induces long-lasting immune training and tolerance in brain microglia that has been shown to persist for at least 6 months . Similarly, LPS preconditioning …
Lipopolysaccharides, from E. coli O55:B5 (LPS，脂多糖) - MCE
心脏功能障碍 (心脏炎症) 是脂多糖 (lps) 诱导脓毒症的常见并发症，其原因是严重的炎症反应。lps 还可引起心脏收缩功能恶化，心脏脂质过氧化增加，导致心脏功能障碍。
Pyroptotic cell corpses are crowned with F-actin-rich ... - Nature
2024年12月4日 · We propose that cells assemble filopodia before cell rupture to serve as a posthumous mark for a cell that has died by gasdermin-induced pyroptosis, or MLKL-induced …
Lipopolysaccharide (LPS)-induced inflammation in RAW264.7
Background: Gram-negative bacterial lipopolysaccharide (LPS) is a major component of inflammation and plays a key role in the pathogenesis of sepsis. According to our previous …
炎症造模少不了的好帮手——脂多糖（LPS） - 知乎专栏
lps信号转导示意图 炎症作为机体免疫应答的重要机制之一，一直是生命科学研究的热点方向，在诸如肿瘤、心脑血管疾病、自身免疫性疾病以及神经退行性疾病等严重威胁人类健康的疾病研 …
MSCs alleviate LPS-induced acute lung injury by inhibiting the
2024年3月11日 · Lipopolysaccharide (LPS)-induced injury promoted macrophage chemotaxis toward lung organoids and enhanced the expression of inflammation-associated genes in …