
Effect of a Soluble Epoxide Hydrolase Inhibitor, UC1728, on LPS …
We tested a potent and orally available inhibitor of sEH for its ability to reduce ocular inflammation in a rabbit LPS-induced model of uveitis. Rabbits were treated by subcutaneous injection with the sEH inhibitor (UC1728, 3 mg/kg), or the vehicle control (PEG400) and uveitis was assessed at 6, 24 and 48 h post-intracameral LPS injection using ...
美国GlpBio - UC-1728 (t-TUCB) | Cas# 948304-40-3
UC-1728 is a potent rabbit soluble epoxide hydrolase (sEH) inhibitor, with an IC50 of 2 nM on rabbit liver. Miotic, fixed pupils are observed in the treated eyes of both groups receiving LPS injections but the difference in pupillary light reflex scores is only significantly increased in the UC-1728/LPS treated group relative to the PBS group ...
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(PDF) Effect of a Soluble Epoxide Hydrolase Inhibitor, UC1728, on LPS ...
2016年1月1日 · Blood levels of UC1728 were a thousand fold higher than the in vitro determined inhibitory potency (IC50) of the compound suggesting a significant degree of inhibition of sEH in the rabbit. The...
(PDF) Effect of a Soluble Epoxide Hydrolase Inhibitor, UC1728, on LPS …
Rabbits were treated by subcutaneous injection with the sEH inhibitor (UC1728, 3 mg/kg), or the vehicle control (PEG400) and uveitis was assessed at 6, 24 and 48 h post-intracameral LPS injection using a modified Hackett-McDonald scoring system. Eyes treated by intra-cameral injection of PBS, or by aseptic preparation served as further controls.
UC-1728 (t-TUCB) | Epoxide Hydrolase Inhibitor | MedChemExpress
UC-1728 is a potent rabbit soluble epoxide hydrolase (sEH) inhibitor, with an IC50 of 2 nM on rabbit liver.
脂多糖(LPS) Lipopolysaaah aricles L8880-北京索莱宝科技有限 …
脂多糖,英文名称Lipopolysaccharides,简称LPS,是革兰氏阴性细菌细胞壁中的一种特有成分,位于细胞壁的最外层并暴露于非荚膜细菌的细胞表面,有利于维持细胞外膜的完整性,保护细菌免受胆汁盐和脂类抗生素的破坏。 结构上,脂多糖由类脂A、核心多糖和O-多糖侧链组成。 其中类脂质A是构成细菌内毒素的主要成分,决定其毒性强弱;而O-多糖侧链在不同细菌间是高度变化的,特异性决定细菌的血清型。 LPS可以引起免疫刺激的级联反应和机体的毒性病理生理活动, …
UC-1728 (t-TUCB) | Cas# 948304-40-3 - GlpBio
UC-1728 is a potent rabbit soluble epoxide hydrolase (sEH) inhibitor, with an IC50 of 2 nM on rabbit liver. Miotic, fixed pupils are observed in the treated eyes of both groups receiving LPS …
- 评论数: 37
Littlest Pet Shop LPS Lot #1728 Owl, #1730 Raccoon, #1732 Seal …
Up for sale is a lot of 4 adorable Littlest Pet Shop figures. They are #1728 the owl, #1730 the raccoon, #1732 the seal and #1729 the cockatoo bird. These have been played with and may show some wear or marks from normal play. They are still in good, clean condition. Please see pictures for details.
GBT 1728-2020(高清) - 道客巴巴
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OWL #1728 - Authentic Littlest Pet Shop - Hasbro LPS - eBay
2024年3月27日 · Find many great new & used options and get the best deals for OWL #1728 - Authentic Littlest Pet Shop - Hasbro LPS at the best online prices at eBay! Free shipping for many products!