Lyophilized liposomes product series are freeze-dried liposomes with various types of lipids and wide range of zeta potentials and different properties. These products should be used by scientists who understand liposome formulation and have the proper equipment to check the size, separate non-encapsulated drugs and do the proper assays.

In rare occasions, liposomes are freeze dried and proliposomes are formed in the presence of a lyoprotectant such as trehalose. Using a lyoprotectant is necessary in order to maintain the size of the liposomes after rehydration. Phosphatidylserine (PS) is a negatively charged molecule.

Lyophilized Anionic Liposomes - Phosphatidylserine (PS)-based DOPS:DOPC (80:20 molar ratio); find Sigma-Aldrich-LPS502 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich

Lipid Composition for LPS-501 Amount (mg/vial) Amount (umol) Molar Ratio Percentage; 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodium salt) 9.03: 11.14: 90: 1,2-dioleoyl-sn-glycero-3-phosphocholine: 0.97: 1.24: 10: Total 10.00 mg/vial 12.38 umol 100; Lipid Composition for LPS-502 Amount (mg/vial) Amount (umol) Molar Ratio Percentage; 1,2 ...

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45-LPS-502-10MG: 10 mg: $1180.00 1/EA: Add To Favorites: Properties; Descriptions; Safety Info. color: white to off-white: composition: DOPS:DOPC (80:20 molar ratio) form: lyophilized powder: mean particle size: 100 nm: Application: • Liposomes are formed upon hydration of the lyophilized formulation. If the lyophilized liposomes are hydrated ...

心脏功能障碍 (心脏炎症) 是脂多糖 (lps) 诱导脓毒症的常见并发症，其原因是严重的炎症反应。lps 还可引起心脏收缩功能恶化，心脏脂质过氧化增加，导致心脏功能障碍。

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lps信号转导示意图 炎症作为机体免疫应答的重要机制之一，一直是生命科学研究的热点方向，在诸如肿瘤、心脑血管疾病、自身免疫性疾病以及神经退行性疾病等严重威胁人类健康的疾病研究过程中，也经常会用到炎症造模这一环节，来评估炎症反应在疾病进程 ...

2016年6月22日 · 结果 通过观察小鼠存活时间，确定腹腔注射最佳染毒剂量为 LPS (2. 5 mg/kg)/ D-GalN (0. 3 g/kg);小鼠染毒后肝组织呈进程性病变，最终发展为肝脏弥漫性坏死，肝细胞核崩解。 与对照组相比，血清 ALT 显著升高 (P ＜0. 001)，IL-6、MCP-1、TNF-α 均在1 h 后达到最高水平 (P ＜0. 001)，然后持续下降。 结论 成功建立 LPS/D-GaIN 诱导小鼠急性肝损伤模型，为探索急性肝损伤的致病机制以及药物干预治疗提供有效的动物模型。