Paper chromatography was used for characterization of 32-P-labeled LPS from different strains of E. coli and Salmonella. The Rf values for LPS varied from 0.27 to 0.75 depending on the amounts of carbohydrates in the molecule. LPS from all strains studied was homogenous except for strain D31 which produced two types of LPS.

1994年9月15日 · C3H/OuJ (Lpsn) macrophages are induced by wild-type LPS, rough LPS, or lipid A to express many genes, including TNF-alpha, TNFR-2, IL-1 beta, IP-10, D3, and D8. C3H/HeJ macrophages failed to induce any of these genes when cultured with wild-type LPS or synthetic lipid A, even when pretreated with IFN-gamma.

脂多糖（Lipopolysaccharide, LPS）是革兰氏阴性细菌外膜的重要成分，对细菌的生存和致病性具有重要影响。 LPS位于细菌外膜的外层，在无荚膜菌株中直接暴露在细胞表面。

2001年7月1日 · Diphosphoryl lipid A derived from the nontoxic LPS of Rhodobacter sphaeroides (RsDPLA) has been shown to be a powerful LPS antagonist in both human and murine cell lines. In addition, RsDPLA also can protect mice against the lethal effects of toxic LPS.

2000年7月15日 · While it did not influence the ability to stimulate cells from wild-type mice, repurification eliminated the ability of LPS to activate cells from C3H/HeJ (Lps d) mice. Additionally, only cell lines transfected with human TLR4, but not human or murine TLR2, acquired responsiveness to both re-extracted LPS and to a protein-free, synthetic ...

1985年12月12日 · The heptoseless mutant of Escherichia coli, E. coli D31 m4, binds C1q and C1 at 0 degrees C and at low ionic strength (I0.07). Under these conditions, the maximum C1q binding averages 3.0 X 10(5) molecules per bacterium, with a Ka of 1.4 X 10(8) M-1.

During standard conditions, 1% of hemolymph could kill 10(3) to 10(4) viable E. coli, strain D31, within 5 min. A lower level of antibacterial activity was induced by injections of a sterile salt solution. The killing of strain D31 followed single-hit kinetics, and increasing rate constants were obtained for increasing amounts of hemolymph.

PA-d31(16：0/18:1） LPC lyso-PC 溶血磷脂酰胆碱 LPC-17：0 LPE lyso-PE 溶血磷脂酰乙醇胺 LPE—17:1 LPS lyso—PSቤተ መጻሕፍቲ ባይዱ 溶血磷酯酰丝氨酸 LPS-17:1 LPA lyso-PA 溶血磷脂酸 LPA-17：0 FFA free fatty acids 豆甾醇酯 Cholesteryl-2,2，3,4，4，6—d6Octadeconate Cho Cholesterol 胆固醇

脂多糖是大多数革兰氏阴性菌外膜的组成部分之一，在保护细菌免受应激、机体产生免疫反应等过程中起着重要作用。 脂多糖（Lipopolysaccharide, LPS） 是革兰氏阴性细菌外壁中的一种特有成分，是由脂质和多糖构成的复合物。 脂多糖很难从细胞壁脱落，当细菌死亡等时它会通过溶解、破坏细胞来脱落，并通过作用于动物细胞等而发挥其毒性。 由于这种性质，它不是细菌分泌到体外的毒素（外毒素），而是不被分泌的“存在于细菌体内的毒素”，所以又被称为 内毒素。 脂多糖 …

lps信号转导示意图 炎症作为机体免疫应答的重要机制之一，一直是生命科学研究的热点方向，在诸如肿瘤、心脑血管疾病、自身免疫性疾病以及神经退行性疾病等严重威胁人类健康的疾病研究过程中，也经常会用到炎症造模这一环节，来评估炎症反应在疾病进程 ...