Injections of Lipopolysaccharide into Mice to Mimic Entrance of ...
To mimic the entrance of bacterial-derived compounds into the host, an endotoxemia model has been adopted in which lipopolysaccharide (LPS), a component of the outer cell wall of Gram …
Lipopolysaccharide-induced lethality and cytokine production in aged mice
This study was designed to define the lipopolysaccharide (LPS) sensitivity of aged mice in terms of lethality and cytokine production and to determine down-regulating responses of …
"Lipopolysaccharide-induced animal models for …
2024年2月15日 · Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1beta …
Neuroinflammation induced by lipopolysaccharide causes …
2019年4月8日 · We found that LPS treatment leads to sickness behavior and cognitive impairment in mice as shown in the Morris water maze and passive avoidance test, and these …
Lipopolysaccharide administration for a mouse model of …
2020年8月7日 · In this study, we evaluated the utility of an intracerebellar injection of lipopolysaccharide (LPS) to generate an animal model of inflammatory CA. We observed that …
Lipopolysaccharide-induced depression-like model in mice: meta …
2023年6月8日 · Numerous LPS-induced depression-like models in mice exist and differ widely in animal characteristics and methodological parameters. Here, we systematically reviewed …
MEK inhibitors increase the mortality rate in mice with LPS …
2023年10月13日 · LPS activates the RAS-RAF-mitogen-activated protein kinase/ERK kinase (MEK)-extracellular-signal-regulated kinase (ERK) signaling cascade in macrophages. The …
LPS Mice: Immune Responses and Brain Health - BiologyInsights
2025年2月12日 · Explore how LPS exposure in mice affects immune responses and brain health, revealing insights into glial activation and cognitive impacts. Lipopolysaccharide (LPS) is a …
Tolerance of mice to lipopolysaccharide is correlated with …
Bacterial endotoxin lipopolysaccharide (LPS) often results in multiple organ failure. However, pre-exposure of mice to a sublethal dose of LPS renders the animal tolerant to a lethal dose of …
Inhibition of NLRP3 inflammasome ameliorates LPS-induced ...
2024年10月1日 · LPS-induced activation of the NLRP3 inflammasome in wild-type mice promotes the progression of PD. The use of MCC950 in wild mice injected with LPS induces activation …