A Langerhans cell (LC) is a tissue-resident macrophage of the skin [2] once thought to be a resident dendritic cell. [3] These cells contain organelles called Birbeck granules.

Apr 26, 2021 · Langerhans cells are a type of immune cell found primarily in the epidermis that have important roles in the stimulation and suppression of the adaptive immune response. …

Jan 14, 2025 · Langerhans cells are a specialized subset of dendritic cells located primarily in the epidermis of the skin. Discovered by Paul Langerhans in 1868, these cells play a crucial role in …

Langerhans cells (LCs) are antigen-presenting dendritic cells (DCs) that reside in epithelia. The best studied example is the LC of the epidermis. By electron microscopy, their identifying …

Langerhans cells (LCs) constitute a cellular immune network across the epidermis. Because they are located at the skin barrier, they are considered immune sentinels of the skin. These …

The Langerhans cells (LCs) originate from the bone marrow and then migrate into the epithelium to perform the function of antigen recognition and presentation. Studies have shown that the …

Jan 31, 2018 · Both keratinocytes and immune cells are essential for sensing the environment and function as a first line of defense against external insults (4). As such, LCs have proven …

Langerhans cells (LCs) are a specialized subset of dendritic cells (DCs) that populate the epidermal layer of the skin. Langerin is a lectin that serves as a valuable marker for LCs in …

Jan 4, 2018 · Langerhans cells (LC) are a unique population of tissue-resident macrophages that form a network of cells across the epidermis of the skin, but which have the ability to migrate …

Langerhans cells (LCs) are the key antigen-presenting cells in the epidermis in normal conditions and respond differentially to environmental and/or endogenous stimuli, exerting either …