2021年6月17日 · Using ex vivo and in vivo experiments, we demonstrate that FYN-TRAF3IP2 and KHDRBS1-LCK activate signaling pathways downstream of the T cell receptor (TCR) complex and confer therapeutic...

2020年7月20日 · We report a previously unknown binding motif in the CD3ε cytoplasmic tail that interacts in a noncanonical mode with the Lck SH3 domain: the receptor kinase (RK) motif. The RK motif is accessible...

CD28 CD was expressed as a glutathione S-transferase (GST) fusion protein and purified after cleavage of the GST fusion partner. Purified recombinant Lck readily phosphorylated CD28WT CD in vitro in the presence of adenosine 5′-triphosphate (ATP) and metal cofactors, as shown by Western blotting analysis with an antiphosphotyrosine antibody ...

This modified GFP is myristoylated and targeted to the plasma membrane (rafts). It was constructed from a parent Lck-GFPN1 construct. The parent Lck sequence was removed and replaced with a new Lck sequence containing two glycine residues at the C-term of Lck, as opposed to an isoleucine and a valine.

《User Manual 用户手册》：因Fusion 16更新了UI，完全采用Davinci内Fusion界面的布局，Davinci Resolve 15.3手册内Fusion手册几乎完全不同，便不列入翻译计划。 加入翻译. 如果你发现了错误，请提PR，或提issue来告知我。

LCK human Fusion Protein 6*His from Proteintech. Produced in E.coli-derived, PET28a, with high quality purity. Cat.No. Ag21475

2004年10月18日 · Our current understanding of the function of Lck and Fyn, the Src-family kinases (SFKs) expressed in T cells, exemplifies this trend. In T cells, the function of SFKs is largely described at a...

2021年6月17日 · Using ex vivo and in vivo experiments, we demonstrate that FYN-TRAF3IP2 and KHDRBS1-LCK activate signaling pathways downstream of the T cell receptor (TCR) complex and confer therapeutic vulnerability to clinically available drugs.

Channel Boolean Material可用于通过数学运算重新映射和修改3D材质的通道。 例如，如果要使用材质的红色通道来控制使用alpha通道的照明模型的标量输入（例如，Blinn.SpecularExponent），则可以在此处重新映射通道。 此外，它允许使用几何物体特定的信息，如纹理空间坐标和法线。 ChannelBooleanMaterial.BackgroundMaterial 背景材质. [橙色，可选的]此输入将接受2D图像或3D材质。 ChannelBooleanMaterial.ForegroundMaterial 前景材 …

2017年6月28日 · CD3ε−Lck interaction was crucial for total TCR phosphorylation. HEK293FT cells with 1G4 TCR and Lck WT or Lck D12N mutant expression were stimulated by α-CD3 antibody (OKT3, eBioscience) for the indicated time, and then cells were lysed for Western blot analysis. Lck had a C-terminal mCherry tag, so it migrated at 70 kDa.