The low-density lipoprotein receptor (LDL-R) is a mosaic protein of 839 amino acids (after removal of 21-amino acid signal peptide) [5] that mediates the endocytosis of cholesterol-rich low …

ldlr，低密度脂蛋白受体相关蛋白是近年来发现的一种细胞表面蛋白,属于一种内吞性受体,系低密度脂蛋白受体基因家族中的一员.由于其能够与多种结构及功能各异的配体相互作用,不仅可以对 …

2024年12月25日 · LDLR (Low Density Lipoprotein Receptor) is a Protein Coding gene. Diseases associated with LDLR include Hypercholesterolemia, Familial, 1 and Homozygous Familial …

Low density lipoprotein receptor (LDLR) is responsible for uptake of cholesterol-carrying lipoprotein particles into cells. The receptor binds lipoprotein particles at the cell surface and …

LDLR is a cell membrane glycoprotein that functions in the binding and internalizing of circulating cholesterol-containing lipoprotein particles. LDLR is ubiquitously expressed and is a key …

The LDLR gene provides instructions for making a protein called the low-density lipoprotein receptor. This receptor binds to particles called low-density lipoproteins (LDLs), which are the …

The role of these receptor proteins in pathogenesis of diverse metabolic risk factors is emerging, rendering them targets of novel therapeutics for metabolic syndrome and atherosclerosis. This …

2024年12月11日 · We established a platform for in-depth functional profiling of LDLR variants regarding cellular LDL uptake and LDLR expression, utilizing robotics and multiplexed high …

6 天之前 · LDLR (low-density lipoprotein receptor) is a long-lived type 1 transmembrane protein that undergoes multiple rounds of internalization and recycling between the cell surface and …

低密度脂蛋白受体 (low-density lipoprotein receptor，LDLR)是血脂载体低密度脂蛋白 (low-density lipoprotein，LDL)代谢途径中的关键介质，其功能紊乱或表达异常与MS各组分的发生发展存 …