
Frontiers | Target Control in Logical Models Using the Domain of ...
We also define the related concept of the logical domain of influence (LDOI) of a node, and develop an algorithm for its identification using an auxiliary network that incorporates the regulatory logic. This way a solution to the target control problem is a set of nodes whose DOI can cover the desired target node states.
we define the DOI and LDOI of a node or multiple nodes and analyze their properties, such as their internal consistency (or lack thereof) and relationship to dynamic attractors. We then define our target control problem and describe our DOI-based target control strategy using greedy randomized adaptive search in node state space.
Target Control in Logical Models Using the Domain of Influence
2018年5月8日 · We also define the related concept of the logical domain of influence (LDOI) of a node, and develop an algorithm for its identification using an auxiliary network that incorporates the regulatory logic. This way a solution to the target control problem is a set of nodes whose DOI can cover the desired target node states.
Genomic Signature of Driver Genes Identified by Target Next
Molecular targeted therapy is now the standard first-line treatment for patients with advanced non-small cell lung cancer (NSCLC). Samples of 1,200 Chinese patients with NSCLC were analyzed through next-generation sequencing to characterize the unique feature of uncommon EGFR mutations and ALK fusio …
Low-dose X-ray radiotherapy–radiodynamic therapy via ... - Nature
2018年3月26日 · Loading a small-molecule IDO inhibitor (IDOi) into the pores and channels of DBP-Hf further enhances therapy in syngeneic mouse models of breast and colorectal cancers with an unprecedented...
Lactobacillus plantarum DR7 improved upper respiratory tract ... - PubMed
DOI: 10.3168/jds.2018-16103 Abstract The aims of this study were to investigate the effects of Lactobacillus plantarum DR7 isolated from bovine milk against upper respiratory tract infections (URTI) and elucidate the possible mechanisms underlying immunomodulatory properties.
Cyberbullying: A concept analysis of defining ... - ScienceDirect
2018年9月1日 · Descriptive analysis revealed five defining attributes of cyberbullying that were shared across all identified definitions. Overall, 15 characteristics were determined to describe the phenomenon. A definition is proposed, and additional influencing factors are discussed.
LDOI 官方题单 - 洛谷
洛谷LDOI官方题单,提供LDOI比赛相关题目和训练资源。
The LDOONIFG flag can be used to indicate that the voltage on LDOI has risen above the launch voltage. In addition to the LDOONIFG being set, an interrupt is also generated when LDOONIE = 1. Similarly, the LDOOFFIFG flag can be used to indicate that the voltage on LDOI has fallen below the launch voltage. In
Group Codes with Low-Density Orthogonal Idempotent
Abstract: We introduce the family of Low-Density Orthogonal Idempotent (LDOI) codes, which are group codes characterized by two-sided ideals of a semisimple group algebra that have an orthogonal idempotent with low Hamming weight. These codes can be thought of as the analog, over a group algebra, of Low-Density Parity-Check (LDPC) codes over ...
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