
MT1-MMP sheds LYVE-1 on lymphatic endothelial cells and
2016年3月1日 · Lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1), a CD44 homologue and the predominant receptor for hyaluronan (HA) on lymphatic endothelial...
Lymph node lymphatic endothelial cells as multifaceted …
2023年1月1日 · LECs from draining LNs can regulate the transport of lymph-borne antigens into the LN parenchyma. Mammalian LN LECs can control the trafficking and sinus-residency of …
Role of lymphatic endothelium specific hyaluronan receptor 1 in …
Lymphatic vessel endothelial hyaluronan receptor 1 (LYVE-1) serves as a prominent marker for lymphatic endothelial cells (LECs) and is pivotal in the process of lymphangiogenesis, a critical …
Generation of pure lymphatic endothelial cells from human …
2015年6月12日 · These hPSC-derived LYVE-1 + PODOPLANIN + cells showed a pure committed LEC phenotype, formed new lymphatic vessels and expressed lymphangiogenic factors at …
ELISA系列 | LYVE-1:区分血管和淋巴管的常用标志物 - 知乎
lyve-1表达于初始淋巴管独特的松散连接处,在白细胞进入时打开的叉指状内皮瓣尖端,其位置指示重要的生理功能。lyve-1通过与dc表面排列的ha结合来介导迁移(图1)。lyve-1更倾向于与 …
Development of the LYVE-1 gene with an acidic-amino-acid-rich …
LYVE-1 has been found to be highly expressed in lymphatic endothelial cells (LECs). LYVE-1 is localized to the luminal and abluminal faces of lymphatic vessels (Banerji et al., 1999). Specific …
Isolation of LYVE-1 + Endothelial Cells from Mouse Embryos
2018年8月5日 · Lymphatic vessel endothelial hyaluronan receptor 1, or LYVE-1, is a type 1 integral membrane glycoprotein expressed by lymphatic endothelial cells (LECs). LYVE-1 is …
LYVE-1/HA在卵巢癌淋巴道转移中作用机制的探索-国家自然科学基 …
我们利用LCM和免疫组化等技术对临床大量卵巢肿瘤标本进行LYVE-1/HA表达分析,阐明该系统与卵巢癌淋巴转移的关系;利用免疫磁珠技术自卵巢癌组织中分离LECs,并分别构建表达LYVE …
MT1-MMP sheds LYVE-1 on lymphatic endothelial cells and …
Here we show that MT1-MMP represents an endogenous negative regulator of lymphangiogenesis that acts through two pathways. It sheds cell surface LYVE-1 on LECs to …
Lymphatic Endothelial Cell Junctions: Molecular Regulation in ...
2022年5月29日 · Lymphatic endothelial cells (LECs) lining lymphatic vessels develop specialized cell-cell junctions that are crucial for the maintenance of vessel integrity ...
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