2010年3月12日 · Skin wounds in adult mice are repaired by Lgr6 stem cells in the hair follicles that flank the damage. After hair morphogenesis, Lgr6 stem cells give rise to epidermal and …

2015年11月10日 · In this article, Kasper and colleagues demonstrate that the hair follicle isthmus, sebaceous gland, and interfollicular epidermis harbor independent self-renewing Lgr6+ …

2021年9月6日 · Thus, our study demonstrated that LGR6 activated a novel β-catenin/TCF7L2/LGR6-positive feedback loop in LGR6 high cervical cancer stem cells …

2013年9月25日 · LGR6 + hair follicle cells predominantly contribute to the maintenance of the junctional zone and sebaceous glands 71, although they show some sporadic contribution to …

2018年10月16日 · Here, we genetically labeled Lgr5- or Lgr6-expressing cells from the hair follicle bulge and interfollicular epidermis (IFE), respectively, and monitored their individual …

2021年7月12日 · Lgr6 marks a population of basally located stem cells in the interfollicular epidermis. Unlike other stem cell compartments in the hair follicle, its contribution to …

Postnatally, Lgr6+ cells generated sebaceous gland and interfollicular epidermis, whereas contribution to hair lineages gradually diminished with age. Adult Lgr6+ cells executed long …

2015年11月10日 · The dynamics and interactions between stem cell pools in the hair follicle (HF), sebaceous gland (SG), and interfollicular epidermis (IFE) of murine skin are still poorly …

2021年9月2日 · Using intravital imaging to capture stem cell dynamics after injury, we show that wound re-epithelialization by Lgr6 stem cells is diminished following loss of nerves. This …

2010年3月12日 · Mammalian epidermis consists of three self-renewing compartments: the hair follicle, the sebaceous gland, and the interfollicular epidermis. We generated knock-in alleles …