HIV-1 management has advanced significantly with antiretroviral therapy (ART), yet challenges persist, including low-level HIV-1 viraemia (LLV). LLV presents a complex scenario, with varied definitions in the literature, reflecting uncertainties in its clinical interpretation.

Our objective was to characterize longitudinal patterns of viraemia and factors associated with viral suppression in people with HIV and low-level viraemia (LLV) during antiretroviral therapy (ART). We included people with HIV in the EuResist Integrated Database with LLV following ART initiation after 2005.

2024年10月17日 · Objective: HIV-1 management has advanced significantly with antiretroviral therapy (ART), yet challenges persist, including low-level HIV-1 viraemia (LLV). LLV presents a complex scenario, with varied definitions in the literature, reflecting uncertainties in …

Background: It is still unclear what might be the best management of people living with HIV (PLWHIV) with low level viremia (LLV) despite being on antiretroviral treatment (ART). Objectives: Aim of our study is to describe the clinical management of PLWHIV with LLV followed in a …

2024年5月9日 · Plasma human immunodeficiency virus-1 (HIV-1) RNA level is an important marker for clinical diagnosis of HIV infection and efficacy evaluation of...

We found the global prevalence of LLV was 13.81%, with its occurrence associated with high baseline VL, AIDS-defining illness, and PI-based regimens at the initiation of ART. Moreover, LLV was strongly associated with an increased risk of VF and all-cause mortality.

2023年11月22日 · Antiretroviral therapy (ART) is the cornerstone of HIV-1 treatment. ART aims to achieve virologic suppression (VS) in people living with HIV (PLWH). Adequate VS could prevent the development of resistance mutations, reduce HIV transmission and improve clinical outcomes [2].

2024年5月22日 · Low-level viremia (LLV) ranging from 50 to 1,000 copies/ml is common in most HIV-1-infected patients receiving antiretroviral therapy (ART). However, the source of LLV and the impact of LLV on the HIV-1 reservoir during ART remain uncertain.

本研究调查了5 394例hiv-1感染/aids患者接受art超过1年后发生llv的比例，以及llv对其后期抗病毒治疗应答的影响，以探讨llv的临床意义。 试读结束， 个人账户登录 后阅读更多内容。

2024年9月17日 · Objective HIV-1 management has advanced significantly with antiretroviral therapy (ART), yet challenges persist, including low-level HIV-1 viraemia (LLV). LLV presents a complex scenario,...