Loop diuretics are a powerful type of diuretic that work by inhibiting the sodium-potassium-chloride (Na+/K+/2Cl) co-transporter in the thick ascending loop of Henle (hence the name loop diuretic), which is located in the kidneys.

The loop diuretics are highly protein bound and therefore enter the tubule primarily by secretion in the proximal tubule, rather than by glomerular filtration [1]. The most commonly used loop diuretics are furosemide, bumetanide, and torsemide, which are sulfonamide derivatives.

2023年8月17日 · Examples of loop diuretics include: Bumetanide (Bumex). Ethacrynic acid (Edecrin). Furosemide (Lasix). Torsemide (Soaanz). Examples of potassium-sparing diuretics include: Amiloride (Midamor). Eplerenone (Inspra). Spironolactone (Aldactone, Carospir). Triamterene (Dyrenium).

Loop diuretics are pharmacological agents that primarily inhibit the Na-K-Cl cotransporter located on the luminal membrane of cells along the thick ascending limb of the loop of Henle. [4] They are often used for the treatment of hypertension and edema secondary to congestive heart failure, liver cirrhosis, or chronic kidney disease.

2023年5月22日 · Loop diuretics are medications used in the management and treatment of fluid overload conditions such as heart failure, nephrotic syndrome or cirrhosis, and hypertension, in addition to edema. This activity reviews the indications, action, and contraindications for loop diuretics as a valuable agent in managing fluid overload and hypertension.

Loop diuretics are medications used to treat fluid overload conditions such as heart failure, nephrotic syndrome or cirrhosis, and hypertension, in addition to edema. Learn about side effects, drug names, and uses.

2023年4月17日 · There are several different classes of diuretics, including carbonic anhydrase inhibitors, loop diuretics, potassium-sparing diuretics, and thiazide diuretics. Each type works in a distinct way and in different parts of the kidney cell (called a nephron).

2022年3月17日 · Loop diuretics are a class of medications used to cause diuresis, or increased urine flow. They differ from other types of diuretics in how they increase urine production. Other diuretic classes include thiazide diuretics, carbonic anhydrase inhibitors, and …

2022年3月11日 · Loop diuretics can be used to treat heart failure, kidney failure, high potassium levels (hyperkalemia), high calcium levels (hypercalcemia), and most types of edema, such as pulmonary edema. Examples of loop diuretics include Bumex (bumetanide) and Lasix (furosemide), as well as Demadex (torsemide).

2023年11月21日 · There are several types of diuretics, each with its own unique mechanism and clinical applications. The main types include: 1. Loop Diuretics. Mechanism of Action: Act on the ascending loop of Henle in the kidney to inhibit sodium, potassium, and chloride reabsorption. 2. Thiazide Diuretics.