Lipoxygenases (EC 1.13.11.-) (LOX) are a family of (non- heme) iron -containing enzymes, more specifically oxidative enzymes, most of which catalyze the dioxygenation of polyunsaturated …

Lysyl oxidase (LOX), also known as protein-lysine 6-oxidase, is an enzyme that, in humans, is encoded by the LOX gene. [5][6] It catalyzes the conversion of lysine residues into its …

Lipoxygenases (LOXs) are dioxygenases that catalyze the formation of corresponding hydroperoxides from polyunsaturated fatty acids such as linoleic acid and arachidonic acid. …

12/15-lipoxygenase (12/15-LOX) is an enzyme, which oxidizes polyunsaturated fatty acids, particularly omega-6 and −3 fatty acids, to generate a number of bioactive lipid metabolites. A …

Cu-dependent lysyl oxidase (LOX) plays a catalytic activity-related, primary role in the assembly of the extracellular matrix (ECM), a dynamic structural and regulatory framework which is …

Lysyl oxidases (LOX) are copper-dependent enzymes that oxidize lysyl and hydroxylysyl residues in collagen and elastin, as a first step in the stabilization of these extracellular matrix proteins …

2019年9月13日 · The lysyl oxidase family comprises five members in mammals, lysyl oxidase (LOX) and four lysyl oxidase like proteins (LOXL1-4). They are copper amine oxidases with a …

2022年12月1日 · Lipoxygenases (LOXs) are non-heme iron (or in some cases manganese) dependent enzymes that catalyze the regioselective dioxygenation of 1 Z,4 Z -pentadiene …

2020年11月1日 · Blockade of Golgi-localized copper transporter ATP7A-mediated copper delivery to LOX family enzymes was demonstrated to significantly reduce tumor growth and cancer …

2 天之前 · The lysyl oxidase (LOX) family, which includes the founding member LOX and four LOX-like enzymes (LOXL1 − 4), was originally identified as a secreted enzyme capable of …