一项基于TCGA数据挖掘的研究（二）-生信自学网 - biowolf.cn
2020年8月7日 · 评分与LUAD患者的临床病理分期相关，免疫核心和StromalScore共享的DEGs主要表现为免疫相关基因的富集，PPI网络与单变量COX回归的交集分析，BTK表达与LUAD患 …
Key genes involved with prognosis were identified in lung ...
2023年6月1日 · By screening the core genes in lung adenocarcinoma (LUAD) with bioinformatics, our study evaluated its prognosis value and role in infiltration process of immune cells. Using …
Identification of potential diagnostic and prognostic biomarkers …
Accumulating evidence has demonstrated that gene alterations play a crucial role in LUAD development, progression, and prognosis. The present study aimed to identify the hub genes …
The prognostic and clinical value of genes associate with immunity …
2024年6月30日 · Exploring differentially expressed genes associated with immune-amino acid metabolism in LUAD could enhance early-stage prediction, facilitate the evaluation of LUAD …
Identifying and Validating Potential Biomarkers of Early Stage …
2021年4月16日 · Lung adenocarcinoma (LUAD) is the most common pathological type of lung cancer. At present, most patients with LUAD are diagnosed at an advanced stage, and the …
Systematic proteome-wide Mendelian randomization using the …
2024年4月4日 · Our study applied these methods to assess causality between plasma proteins and LUAD. Furthermore, we employed a two-step MR to quantify the proportion of risk factors …
Identification of the key genes and characterizations of Tumor …
2020年6月16日 · In LUAD, the PPI network contained 233 genes, of which 35 were immune-related genes, and one module with score > 10 was identified from the PPI network (Figure …
Identifying and Validating Potential Biomarkers of Early Stage …
2021年4月16日 · A PPI network consisting of 300 nodes and 1140 edges was constructed, and a significant module including 15 genes was identified. Elevated expression of ASPM, CCNB2, …
Identification Of PPIA As A Prognostic Biomarker Of Lung …
Results: The expression of PPIA in LUAD tissues was significantly upregulated than those in adjacent normal tissues. High PPIA mRNA expression was associated with lymph node …
FKBP3, a poor prognostic indicator, promotes the progression of LUAD …
2024年6月28日 · Immunohistochemical staining results showed that FKBP3 was highly located in cytoplasm and membrane of cells in LUAD tissues. PPI network analysis results showed that …