Lymphocyte Subset Normal Range Chart . A. Pediatric Normal Range Chart . CD3/8. Ratio. B. Adult Normal Range Chart . References: 1. Shearer WT et al. 2003. Lymphocyte subsets in healthy children from birth through 18 years of age: The pediatric AIDS Clinical Trials Group P1009 study. J Allergy Clin Immunol. 112:973-80 2.

T lymphocytes play a pivotal role in both cell-mediated and humoral immune responses of the adaptive immune system. These functions are carried out by T lymphocytes that interact with antigen through the TCR.

Lymphocytes in peripheral blood (circulation) are heterogeneous and can be broadly classified into T cells, B cells, and natural killer (NK) cells. There are various subsets of each of these individual populations with specific cell-surface markers and function.

Flow cytometric immunophenotyping of peripheral blood lymphocyte subsets is a powerful tool for evaluating cellular immunity and monitoring immune-mediated diseases. The numbers and proportions of blood lymphocyte subsets are influenced by factors such as …

2013年8月2日 · Analysis of peripheral blood lymphocyte subsets has become an essential tool in the evaluation of immunological and pathological disorders. Establishment of a normal reference range is fundamental for precise elucidation of immunophenotyping data based on age, gender, ethnicity, genetic differences, and environmental factors.

2021年8月9日 · Lymphocytes can be broadly subdivided into three major populations on the basis of functional and phenotypic differences: B lymphocytes (B cells), T lymphocytes (T cells), and natural killer (NK) cells.

Useful for assessing primary T-cell immunodeficiency disorders. Indicates whether a test has been approved by the New York State Department of Health. This test is New York state approved. Patient Preparation Instructions patient must follow before/during specimen collection. Collect Specimen type to collect.

This assay provides absolute cell counts and percentages for CD4, CD8 and CD3 T cell subsets. All lymphocyte subset panels offered: T cell subsets CD4/CD8 only, counts [TCS48] - CD4, CD8 T cell subsets CD3/CD4/CD8, counts [TCSA] - CD4, CD8, CD3 Lymphocyte subsets, T and B cell counts [TCSP] - CD4, CD8, CD3, CD19 Lymphocyte subsets, T, B, NK ...

LLS: Pediatric reference values taken from Scandinavian Journal of Immunology 2012; 75, 436-444. Adult ranges were developed in-lab at Legacy Lab Services.

Methods: We performed dual platform flow cytometry to determine reference ranges for lymphocyte subsets (CD3, CD4, CD8, CD19 [B cells] and CD16+CD56+ [Natural Killer - NK cells]) in 50 adolescents (age range: 12-18) and 100 adults (age range: 21-67) along with T cell maturation, activation and co-stimulatory molecules in healthy multiracial ...