Lysozyme (EC 3.2.1.17, muramidase, N-acetylmuramide glycanhydrolase; systematic name peptidoglycan N-acetylmuramoylhydrolase) is an antimicrobial enzyme produced by animals …

Lysozyme is a small, stable enzyme, making ideal for research into protein structure and function. Brian Matthews at the University of Oregon has performed a remarkable series of …

2024年7月27日 · Explore the structure, sources, and diverse applications of lysozyme, including its role in immune response and potential therapeutic uses. Discovered over a century ago, …

Lysozyme is an enzyme present in both animal and human lacrimal gland secretions (or tears), gastric secretions, nasal mucus, and egg white. It is discovered in 1921 by Sir Alexander …

In physiological conditions, lysozyme is folded into a compact, globular structure with a long cleft in the protein surface. This cleft is the active site involved in binding to the bacterial …

1996年8月21日 · Origin of carbohydrate recognition specificity of human lysozyme revealed by affinity labeling.

Human lysozyme is a globular protein with antimicrobial properties with tendencies to fibrillate and hence is known as a fibril-forming protein. Therefore, its behavior under different ambient …

Enzymes are thought to use their ordered structures to facilitate catalysis. A corollary of this theory suggests that enzyme residues involved in function are not optimized for stability. We …

1999年12月28日 · Hen egg-white lysozyme has been crystallized at slightly alkaline pH using 2-methyl-2,4-pentanediol (MPD) as the precipitant. The crystals are nearly isomorphous to …

The structure of lysozyme is relatively simple, with a beta-barrel shape that is common to many globular proteins. The protein has a hydrophobic core, meaning that it is largely composed of …