2003年3月1日 · ;Mannose 6-phosphate (M6P) receptors (the CD-MPR and CI-MPR) are type-I integral membrane glycoproteins that constitute the family of p-type lectins. They bind to M6P …

2019年5月7日 · PMI是一种锌依赖性酶，可催化甘露糖6磷酸（M6P）和果糖6磷酸（F6P）之间的可逆异构化，可能是通过形成顺式烯二醇中间体。 假设该反应涉及M6P的开环，质子从C2原 …

2022年6月23日 · Ultimately, we successfully deliver several variants that separately exhibit both enhanced preference and catalytic efficiency to three widespread C6 sugar-phosphates, …

2024年6月1日 · To minimize the byproducts formation, one mannose-6-phosphate specific phosphatase (M6PP) was identified through screening and characterization of phosphatases. …

Mannose-6-phosphate (M6P) is a molecule bound by lectin in the immune system. M6P is converted to fructose 6-phosphate by mannose phosphate isomerase. M6P is a key targeting …

Mannose-6-phosphate is an N-linked oligosaccharide generated by enzymes present in the cis-Golgi cisterna. It is formed specifically on proteins destined for the lysosome.

Download scientific diagram | The representative binding conformation and binding energy (ΔG°) of the WT and mutants to M6P, F6P, and G6P a–c represented that of WT, L18K and MM3 for …

The cation-independent mannose 6-phosphate receptor is a multifunctional protein which binds at the cell surface to two distinct classes of ligands, the mannose 6-phosphate (M6P) bearing …

In this study, we found that probiotics may reduce the production of NO and reduce intestinal inflammation by downregulating the NOS2 gene; downregulation of GAD1 gene reduces …

The explanation of how are the lysosomal enzymes accurately recognized and selected over many other proteins in the trans-Golgi network relies on being tagged with a unique marker: …