The mannose 6-phosphate receptors (MPRs) are transmembrane glycoproteins that target enzymes to lysosomes in vertebrates. [1] Mannose 6-phosphate receptors bind newly …

2024年12月25日 · M6PR (Mannose-6-Phosphate Receptor, Cation Dependent) is a Protein Coding gene. Diseases associated with M6PR include Pompe Disease and Niemann-Pick …

阳离子非依赖性甘露糖 6-磷酸受体 (CI-M6PR) 是一种普遍存在的跨膜受体，其主要细胞内作用是将携带甘露糖 6-磷酸部分的酶引导至溶酶体区室。 最近，该受体的小膜结合部分似乎与许多 …

2024年1月1日 · The cation-independent mannose 6-phosphate receptor (CI-M6PR) is a ubiquitous transmembrane receptor whose main intracellular role is to direct enzymes carrying …

2018年5月16日 · We propose that targeting kinesin motor KIF13A and M6PR has great potential for vaccine design and efficient immunotherapy.

CI-M6PR has been proposed as an alternative pathway to induce cell death through the delivery of lymphocyte granule toxins. Several studies indicate that CI-M6PR expressed at the cell …

2017年4月25日 · Mannose-6-phosphate receptor (M6PR) that facilitates cellular uptake of M6P-bearing proteins, including serine-protease granzyme-B (Gzm-B) has an important role in...

In the fields of biochemistry and cell biology, the cation-dependent mannose-6-phosphate receptor (CD-MPR) also known as the 46 kDa mannose 6-phosphate receptor is a protein that …

Sortilin is a new alpha-Gal A receptor expressed in renal endothelial cells and that this receptor together with the M6PR is able to internalize circulating alpha-Gal A. Mannose receptor (MR) …

P 型凝集素通过将含 6-磷酸甘露糖的酸性水解酶从高尔基复合体特异性转运至溶酶体，在溶酶体功能中发挥关键作用。 编码的蛋白质作为同型二聚体发挥作用，需要二价阳离子才能与配体结 …